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 Home cDNA Clone TrueORF All SKP1 ORF Clones
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SKP1 (NM_006930) Human cDNA ORF Clone

Specifications Citations (1) Clone of Other Species Product Documents
Cat. No. Description Price Availability  
RC206509 Myc-DDK-tagged ORF clone of Homo sapiens S-phase kinase-associated protein 1 (SKP1), transcript variant 1 as transfection-ready DNA, 10µg
$380
 In Stock
RC506509 Myc-DDK-tagged ORF clone of Homo sapiens S-phase kinase-associated protein 1 (SKP1), transcript variant 1 as 200 ug transfection-ready DNA $500 2~3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248
$198		 In Stock

$50 off anti-DDK and other anti-tag antibodies till June 30th, 2013

The same insert cloned in Lenti and other vectors is also available.

Cat. No. Description Vector Price Availability  
RC206509L1 Lenti ORF clone of Human S-phase kinase-associated protein 1 (SKP1), transcript variant 1 , Myc-DDK-tagged

$750 2 Weeks
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $360 In Stock
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Also for SKP1 (NM_006930)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody Service
TrueORF Data for RC206509
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence 		ORF Size: 483 bp
Predicted Protein MW: 17.9 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Druggable Genome
Protein Pathways: Cell cycleOocyte meiosisUbiquitin mediated proteolysisWnt signaling pathwayTGF-beta signaling pathway
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_006930.2, NP_008861
 RefSeq Size: 2172 RefSeq ORF: 483
Synonyms : EMC19; OCP-II; OCP2; p19A; SKP1A; TCEB1L
LocusID: 6500 Cytogenetic: 5q31 Domains: Skp1
Summary: This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008].

 
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