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Home cDNA Clone TrueORF All TXNRD2 ORF Clones

TXNRD2 (NM_006440) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC220848 TXNRD2 (Myc-DDK-tagged)-Human thioredoxin reductase 2 (TXNRD2), nuclear gene encoding mitochondrial protein, (Note, selenocysteine protein, internal stop codon, see reference data summary), 10µg
$630
In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification

The same insert cloned in Lenti and other vectors is also available.

Cat. No. Description Vector Price Availability  
RC220848L2 Lenti-ORF clone of TXNRD2 (mGFP-tagged)-Human thioredoxin reductase 2 (TXNRD2), nuclear gene encoding mitochondrial protein, (Note, selenocystein protein, internal stop codon, see summary), (10ug)

1100 7 Weeks
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $390 In Stock
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TrueORF Data for RC220848
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1647 bp
Predicted Protein MW: 57 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Druggable Genome
Protein Pathways: Pyrimidine metabolism

Reference Data
RefSeq: NM_006440.4, NP_006431
RefSeq Size: 2127 RefSeq ORF: 1575
Synonyms : SELZ; TR; TR-BETA; TR3; TRXR2
LocusID: 10587 Cytogenetic: 22q11.21 Domains: pyr_redox, pyr_redox_dim
Summary: This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2013].

 

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