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Home cDNA Clone TrueORF All SF3B4 ORF Clones

SF3B4 (NM_005850) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC210352 SF3B4 (Myc-DDK-tagged)-Human splicing factor 3b, subunit 4, 49kDa (SF3B4), 10µg   
$560
In Stock
RG210352 SF3B4 (GFP-tagged) - Human splicing factor 3b, subunit 4, 49kDa (SF3B4), (10ug) $610 2-3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC510352 0 4 weeks
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Clone Modification
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The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
RG210352 SF3B4 (GFP-tagged) - Human splicing factor 3b, subunit 4, 49kDa (SF3B4), (10ug)

$610 3 Weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
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TrueORF Data for RC210352
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1275 bp
Predicted Protein MW: 44.4 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Pathways: Spliceosome

Reference Data
RefSeq Explanation: NM_005850.4, NP_005841 RefSeq Size: 2001 RefSeq ORF: 1275
Synonyms : AFD1; Hsh49; SAP49; SF3b49
LocusID: 10262 Cytogenetic: 1q21.2 Domains: rrm
Gene Summary: This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq, Jul 2008].

 

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