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Home cDNA Clone TrueORF All ILK ORF Clones

ILK (NM_004517) Human Mutant ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC402741 ILK Mutant (A262V), Myc-DDK-tagged ORF clone of Homo sapiens integrin-linked kinase (ILK), transcript variant 1 as transfection-ready DNA, 10µg
$680
In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for ILK (NM_004517)
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TrueORF Data for RC402741
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1356 bp
Predicted Protein MW: 49.7 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map
OTI Annotation:
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Protein KinaseDruggable Genome
Protein Pathways: PPAR signaling pathwayFocal adhesionEndometrial cancer

Reference Data
RefSeq: , NP_004508
RefSeq Size: 1356 RefSeq ORF: 1359
Synonyms : HEL-S-28; ILK-1; ILK-2; P59; p59ILK
LocusID: 3611 Cytogenetic: 11p15.4 Domains: pkinase, TyrKc, ANK, S_TKc
Summary: This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013].

 

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