Home All Cancer Mutant Clones STK11 Mutants

Description of the mutations of STK11 (NM_000455) Mutants

Keys for Mutation Description

A.A. substitution
Truncation
NT deletion
NT insertion

R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted

SKU	Mutation Description	Affected Codon#	Affected NT#	Description	Effect
RC400276	Y60fs*1	60	c.180	delC	Frameshift
RC400268	D194N	194	c.580	G>A	Missense
RC400269	D194Y	194	c.580	G>T	Missense
RC400270	P279fs*6	279	c.837	delC	Frameshift
RC400271	G171S	171	c.511	G>A	Missense
RC400272	F354L	354	c.1062	C>G	Missense
RC400273	P281L	281	c.842	C>T	Missense
RC400274	P281fs*6	281	c.842	delC	Frameshift
RC400275	V66M	66	c.196	G>A	Missense
RC400277	R304W	304	c.910	C>T	Missense
RC400278	T32T	32	c.96	C>G	Missense
RC400279	F263fs*22	263	c.787_790	delTTGT	Frameshift
RC400280	E57fs*7	57	c.169	delG	Frameshift
RC400281	Y272Y	272	c.816	C>T	Missense
RC400282	Q170*	170	c.508	C>T	Truncation
RC400283	Q37*	37	c.109	C>T	Truncation
RC400284	W332*	332	c.996	G>A	Truncation
RC402189	K44X	44	130	A>T	Gonadotrophin-independent precocious puberty
RC402190	Y49X	49	147	C>A	Peutz-Jeghers syndrome
RC402191	E57X	57	169	G>T	Peutz-Jeghers syndrome
RC402192	Y60X	60	180	C>G	Peutz-Jeghers syndrome
RC402193	Y60X	60	180	C>A	Peutz-Jeghers syndrome
RC402194	L67R	67	200	T>G	Peutz-Jeghers syndrome
RC402195	L67P	67	200	T>C	Peutz-Jeghers syndrome
RC402196	E70X	70	208	G>T	Peutz-Jeghers syndrome
RC402197	K81X	81	241	A>T	Peutz-Jeghers syndrome
RC402198	K84X	84	250	A>T	Peutz-Jeghers syndrome
RC402199	R86X	86	256	C>T	Peutz-Jeghers syndrome
RC402200	Q100X	100	298	C>T	Peutz-Jeghers syndrome
RC402201	K108R	108	323	A>G	Peutz-Jeghers syndrome
RC402202	Q112X	112	334	C>T	Peutz-Jeghers syndrome
RC402203	Y118X	118	354	C>A	Peutz-Jeghers syndrome
RC402204	Y118X	118	354	C>G	Peutz-Jeghers syndrome
RC402205	Q123X	123	367	C>T	Peutz-Jeghers syndrome
RC402206	Y126X	126	378	T>G	Peutz-Jeghers syndrome
RC402207	E130X	130	388	G>T	Peutz-Jeghers syndrome
RC402208	C132X	132	396	C>A	Peutz-Jeghers syndrome
RC402209	M136R	136	407	T>G	Peutz-Jeghers syndrome
RC402210	Q137X	137	409	C>T	Peutz-Jeghers syndrome
RC402211	E138X	138	412	G>T	Peutz-Jeghers syndrome
RC402212	Q152X	152	454	C>T	Peutz-Jeghers syndrome
RC402213	Y156X	156	468	C>G	Peutz-Jeghers syndrome
RC402214	F157S	157	470	T>C	Peutz-Jeghers syndrome
RC402215	D162N	162	484	G>A	Peutz-Jeghers syndrome
RC402216	G163D	163	488	G>A	Peutz-Jeghers syndrome
RC402217	L164M	164	490	C>A	Peutz-Jeghers syndrome
RC402218	E165X	165	493	G>T	Peutz-Jeghers syndrome
RC402219	L167R	167	500	T>G	Peutz-Jeghers syndrome
RC402220	Q170P	170	509	A>C	Peutz-Jeghers syndrome
RC402221	H174R	174	521	A>G	Peutz-Jeghers syndrome
RC402222	D176N	176	526	G>A	Peutz-Jeghers syndrome
RC402223	I177N	177	530	T>A	Peutz-Jeghers syndrome
RC402224	N181T	181	542	A>C	Peutz-Jeghers syndrome
RC402225	N181Y	181	541	A>T	Peutz-Jeghers syndrome
RC402226	L182P	182	545	T>C	Peutz-Jeghers syndrome
RC402227	L184P	184	551	T>C	Peutz-Jeghers syndrome ?
RC402228	Q214X	214	640	C>T	Peutz-Jeghers syndrome
RC402229	Q220X	220	658	C>T	Peutz-Jeghers syndrome
RC402230	T230P	230	688	A>C	Peutz-Jeghers syndrome
RC402231	S232P	232	694	T>C	Peutz-Jeghers syndrome
RC402232	I238F	238	712	A>T	Peutz-Jeghers syndrome ?
RC402233	W239C	239	717	G>C	Peutz-Jeghers syndrome ?
RC402234	S240X	240	719	C>A	Peutz-Jeghers syndrome
RC402235	G242E	242	725	G>A	Peutz-Jeghers syndrome
RC402236	G242v	242	725	G>T	Peutz-Jeghers syndrome ?
RC402237	G242W	242	724	G>T	Peutz-Jeghers syndrome
RC402238	L245R	245	734	T>G	Peutz-Jeghers syndrome
RC402239	Y246X	246	738	C>G	Peutz-Jeghers syndrome
RC402240	G251S	251	751	G>A	Peutz-Jeghers syndrome
RC402241	Y253X	253	759	C>A	Peutz-Jeghers syndrome
RC402242	E256A	256	767	A>C	Peutz-Jeghers syndrome
RC402243	E256X	256	766	G>T	Peutz-Jeghers syndrome
RC402244	L285P	285	854	T>C	Peutz-Jeghers syndrome
RC402245	K287T	287	860	A>C	Peutz-Jeghers syndrome ?
RC402246	R297S	297	891	G>T	Peutz-Jeghers syndrome
RC402247	R297K	297	890	G>A	Peutz-Jeghers syndrome
RC402248	R304P	304	911	G>C	Peutz-Jeghers syndrome
RC402249	H306Y	306	916	C>T	Peutz-Jeghers syndrome
RC402250	W308C	308	924	G>T	Peutz-Jeghers syndrome
RC402251	W308X	308	923	G>A	Peutz-Jeghers syndrome
RC402252	P324L	324	971	C>T	Peutz-Jeghers syndrome
RC402253	K416X	416	1246	A>T	Peutz-Jeghers syndrome

Over 1000 citations of OriGene cDNA clones

Description of the mutations of STK11 (NM_000455) Mutants