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15-PGDH inhibits hepatocellular carcinoma growth through 15-keto-PGE2/PPAR?-mediated activation of p21WAF1/Cip1 Oncogene doi:10.1038/onc.2013.69 [PTGR2 ]

A Modified Form of Diphthamide Causes Immunotoxin Resistance in a Lymphoma Cell Line with a Deletion of the WDR85 Gene J. Biol. Chem., Apr 2013; 288: 12305 - 12312. [WDR85]

A New Signaling Pathway (JAK-Fes-phospholipase D) That Is Enhanced in Highly Proliferative Breast Cancer Cells J. Biol. Chem., Apr 2013; 288: 9881 - 9891. [FES]

Androgen receptor inclusions acquire GRP78/BiP to ameliorate androgen-induced protein misfolding stress in embryonic stem cells Cell Death and Disease 4, e607 doi:10.1038/cddis.2013.122 [GRP78]

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Home All Cancer Mutant Clones PKN3 Mutants

Description of the mutations of PKN3 (NM_013355) Mutants

Quote for the whole set

Keys for Mutation Description

A.A. substitution
Truncation
NT deletion
NT insertion

R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted

SKU	Mutation Description	Affected Codon#	Affected NT#	Description	Effect
RC403205	W346X	346	1038	G>A	Poenil proein defiieny

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