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15-PGDH inhibits hepatocellular carcinoma growth through 15-keto-PGE2/PPAR?-mediated activation of p21WAF1/Cip1 Oncogene doi:10.1038/onc.2013.69 [PTGR2 ]
A Modified Form of Diphthamide Causes Immunotoxin Resistance in a Lymphoma Cell Line with a Deletion of the WDR85 Gene J. Biol. Chem., Apr 2013; 288: 12305 - 12312. [WDR85]
A New Signaling Pathway (JAK-Fes-phospholipase D) That Is Enhanced in Highly Proliferative Breast Cancer Cells J. Biol. Chem., Apr 2013; 288: 9881 - 9891. [FES]
Androgen receptor inclusions acquire GRP78/BiP to ameliorate androgen-induced protein misfolding stress in embryonic stem cells Cell Death and Disease 4, e607 doi:10.1038/cddis.2013.122 [GRP78]
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HomeAll Cancer Mutant ClonesMYCN Mutants

Description of the mutations of MYCN (NM_005378) Mutants

Quote for the whole set

Keys for Mutation Description

A.A. substitution
Truncation
NT deletion
NT insertion
R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted

 

SKUMutation DescriptionAffected Codon#Affected NT#DescriptionEffect
RC402779 E73X73217G>TFeingold syndrome
RC402780 W77X77231G>AFeingold syndrome
RC402781 G151X151451G>TFeingold syndrome
RC402782 S221X221662C>AFeingold syndrome
RC402783 R322X322964C>TFeingold syndrome
RC402784 R373X3731117C>TFeingold syndrome
RC402785 R382H3821145G>AFeingold syndrome
RC402786 R393H3931178G>AFeingold syndrome
RC402787 R393S3931177C>AFeingold syndrome
RC402788 R394H3941181G>AFeingold syndrome
RC402789 P409L4091226C>TFeingold syndrome

 

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