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HomeAll Cancer Mutant ClonesMET Mutants

Description of the mutations of MET (NM_000245) Mutants

Keys for Mutation Description

A.A. substitution
Truncation
NT deletion
NT insertion
R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted

 

SKUMutation DescriptionAffected Codon#Affected NT#DescriptionEffect
RC400334 Y1230H1230c.3688T>CMissense
RC400335 E168D168c.504G>TMissense
RC400336 N375S375c.1124A>GMissense
RC400337 R970C970c.2908C>T Missense
RC400329 L982_D1028del982c.2942_3082del141deletion
RC400330 M1250T1250c.3749T>CMissense
RC400331 T1173I1173c.3518C>T Missense
RC400332 V1220D1220c.3659T>AMissense
RC400333 Y1230C1230c.3689A>GMissense

 

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