Description of the mutations of MET (NM_000245) Mutants
Keys for Mutation Description
A.A. substitution
Truncation
NT deletion
NT insertion
Truncation
NT deletion
NT insertion
R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted
| SKU | Mutation Description | Affected Codon# | Affected NT# | Description | Effect |
| RC400334 | Y1230H | 1230 | c.3688 | T>C | Missense |
| RC400335 | E168D | 168 | c.504 | G>T | Missense |
| RC400336 | N375S | 375 | c.1124 | A>G | Missense |
| RC400337 | R970C | 970 | c.2908 | C>T | Missense |
| RC400329 | L982_D1028del | 982 | c.2942_3082 | del141 | deletion |
| RC400330 | M1250T | 1250 | c.3749 | T>C | Missense |
| RC400331 | T1173I | 1173 | c.3518 | C>T | Missense |
| RC400332 | V1220D | 1220 | c.3659 | T>A | Missense |
| RC400333 | Y1230C | 1230 | c.3689 | A>G | Missense |
