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HomeAll Cancer Mutant ClonesMAP2K2 Mutants

Description of the mutations of MAP2K2 (NM_030662) Mutants

Keys for Mutation Description

A.A. substitution
Truncation
NT deletion
NT insertion
R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted

 

SKUMutation DescriptionAffected Codon#Affected NT#DescriptionEffect
RC403497 F57L57171T>ACrdio-fio-uneous syndrome
RC403498 F57C57170T>GCrdio-fio-uneous syndrome
RC403499 F57V57169T>GCrdio-fio-uneous syndrome
RC403500 F57I57169T>ACrdio-fio-uneous syndrome
RC403501 K61T61182A>CCrdio-fio-uneous syndrome
RC403502 K61E61181A>GCrdio-fio-uneous syndrome
RC403503 A62P62184G>CCrdio-fio-uneous syndrome
RC403504 P128R128383C>GCrdio-fio-uneous syndrome
RC403505 G132V132395G>TCrdio-fio-uneous syndrome
RC403506 Y134C134401A>GCrdio-fio-uneous syndrome
RC403507 Y134H134400T>CCrdio-fio-uneous syndrome
RC403508 K273R273818A>GCrdio-fio-uneous syndrome

 

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