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Over 1000 citations of OriGene cDNA clones
Activation of the Ca2+-sensing receptor increases renal claudin-14 expression and urinary Ca2+ excretion Am J Physiol Renal Physiol, Mar 2013; 304: F761 - F769. [Cldn14]
An SRF/miR-1 axis regulates NCX1 and Annexin A5 protein levels in the normal and failing heart Cardiovasc Res, Mar 2013; 10.1093/cvr/cvt042. [JunD]
Betaglycan Alters NFB-TGFß2 Cross Talk to Reduce Survival of Human Granulosa Tumor Cells Mol. Endocrinol., Mar 2013; 27: 466 - 479. [SMAD3]
Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression Carcinogenesis, Mar 2013; 34: 550 - 559. [cathepsin B]
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HomeAll Cancer Mutant ClonesEPHX1 Mutants

Description of the mutations of EPHX1 (NM_000120) Mutants

Quote for the whole set

Keys for Mutation Description

A.A. substitution
Truncation
NT deletion
NT insertion
R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted

 

SKUMutation DescriptionAffected Codon#Affected NT#DescriptionEffect
RC401073 R43T43128G>CInresed EPHX1 iviy, ssoiion wih
RC401074 W97X97290G>APoenil proein defiieny
RC401075 Y113H113337T>CEpoxide hydrolse defiieny, ssoiion wih
RC401076 H139R139416A>GPreelmpsi, ssoiion wih

 

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