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HomeAll Cancer Mutant ClonesCDH1 Mutants

Description of the mutations of CDH1 (NM_004360) Mutants

Keys for Mutation Description

A.A. substitution
Truncation
NT deletion
NT insertion
R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted

 

SKUMutation DescriptionAffected Codon#Affected NT#DescriptionEffect
RC400181 T263fs*3263c.786_794CACCCAGGA>TFrameshift
RC400182 V82fs*1380c.240_241insGGTGFrameshift
RC400183 D370H370c.1108G>CMissense
RC400184 T399fs*17399c.1196_1199delCTGAFrameshift
RC400187 G434fs*434c.1302_1303insAFrameshift
RC400185 A634V634c.1901C>TMissense
RC400186 L14fs*14c. 41delTFrameshift
RC400188 L436fs*436c.1306_1307delTTFrameshift

 

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