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HomeAll Cancer Mutant ClonesAURKA Mutants

Description of the mutations of AURKA (NM_198433) Mutants

Keys for Mutation Description

A.A. substitution
NT deletion
NT insertion
R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted


SKUMutation DescriptionAffected Codon#Affected NT#DescriptionEffect
RC403785 F31I3191T>AOesophageal cancer, association with
RC403786 v57I57169G>AOesophageal cancer, association with
RC403787 Q394X3941180C>TPotential protein deficiency


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