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OriGene Antibodies in recent publications
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Activation of Transcription Factor Nrf2 Signalling by the Sphingosine Kinase Inhibitor SKI-II Is Mediated by the Formation of Keap1 Dimers PLoS ONE, Feb 2014. [Keap1]

CD4+ Memory Stem Cells (TSCM) are Infected by HIV-1 in a Manner Regulated in Part by SAMHD1 Expression J. Virol., Feb 2014. [SAMHD1]

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TruePLEX™ VEGFA Single-plex Reagent Set

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Home >> TruePlex >> AM100108
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Catalog No. Product Description Amount Price Shipping *
AM100108 TruePLEX™ VEGFA Single-plex Reagent Set (Gene ID: 7422) 96 rxn $229 2 weeks
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Product Details: Single-plex reagent set for the measurement of VEGFA in cell culture supernatant, human sera, or human plasma in conjunction with xMAP™ technology from Luminex Corporation. These reagents may be combined with other Growth Factor Panel single-plex reagent sets to create a custom multiplex. The TruePLEX™ Extracellular Core Reagent Kit (AM100097) kit is required to run this assay.
Standard Curves
11 plex standard curves
Gene Name: Vascular endothelial growth factor A
Research Focus: Oncology
Platform: Luminex xMAP®
Product Configuration: Single-plex can be mixed with up to 9 other single-plexes
Product Type: Single-plex reagent set
Sample Type: serum, plasma, tissue culture supernatant
Sample Volume: 50 µl
Species Reactivity: Human
Components: Beads, detection antibody, standards
Performance Summary
Performance Summary
Sensitivity Specification: 21 pg/ml
Normal Mean and Range Serum Samples: 107.7 (4.0 - 393)
Normal Mean and Range Plasma Samples: 79.4 (0.29 - 371)
Intra-assay CV – Standards (specification): <15%
Intra-assay CV – Serum/Plasma (specification): <20%
Inter-assay CV – Serum/Plasma (specification): <20%
Recovery (specification) : 80-120%
Linearity (specification): 80-120%
Cross Reactivity: Negligible
Background Info: This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008].
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