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Home TrueClone ACACA Clone

ACACA (NM_198834) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC307787 ACACA (untagged)-Human acetyl-CoA carboxylase alpha (ACACA), transcript variant 1 (10ug) NM_198834.1, 10ug $2500 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA307853 Rabbit monoclonal antibody against Acetyl CoA Carboxylase 1 (ACC1)(clone EPR4971), 100ul $325 3-7 Days
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 8000 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: ORF of this clone was fully sequenced and it matches with NM_198834.1.
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Druggable Genome
Protein Pathways: Fatty acid biosynthesisPyruvate metabolismPropanoate metabolismMetabolic pathwaysInsulin signaling pathway
Reference Data
RefSeq: NM_198834.1, NP_942131
RefSeq Size: 10018 RefSeq ORF: 7152
Synonyms : ACAC; ACACAD; ACC; ACC1; ACCA
LocusID: 31 Cytogenetic: 17q21
Summary: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Transcript Variant: This variant (1) encodes the longest isoform (1).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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