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Home TrueClone ADAM12 Clone

ADAM12 (NM_021641) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC112913 ADAM12 (untagged)-Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 2 (10ug), NM_021641.2, 10ug $1330 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA302969 Goat Polyclonal Antibody against ADAM12, 100ug $325 3-7 Days
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 3750 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Secreted ProteinTransmembraneProteaseDruggable Genome
Reference Data
RefSeq: NM_021641.2, NP_067673
RefSeq Size: 3355 RefSeq ORF: 2217
Synonyms : ADAM12-OT1; CAR10; MCMP; MCMPMltna; MLTN; MLTNA
LocusID: 8038 Cytogenetic: 10q26
Summary: This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form. [provided by RefSeq, Jan

Transcript Variant: This variant (2) lacks multiple 3' coding exons and contains an alternate 3' terminal exon, resulting in a different 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2, also known as ADAM12-S) has a distinct C-terminus and is shorter than isoform 1.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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