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Home TrueClone PAK6 Clone

PAK6 (NM_020168) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC113203 PAK6 (untagged)-Human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1 (10ug), NM_020168.3, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA306114 Rabbit Polyclonal PAK6 Antibody, 100ug $325 3-7 Days
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Click here for the corresponding kinase deficient mutant clone.
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 4470 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Protein KinaseDruggable Genome
Protein Pathways: ErbB signaling pathwayAxon guidanceFocal adhesionT cell receptor signaling pathwayRegulation of actin cytoskeletonRenal cell carcinoma
Reference Data
RefSeq: NM_020168.3, NP_064553
RefSeq Size: 3889 RefSeq ORF: 2046
Synonyms : PAK5
LocusID: 56924 Cytogenetic: 15q14 Domains: PBD, pkinase, TyrKc, S_TKc
Summary: This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013].

Transcript Variant: This variant (1) encodes isoform 1. Variants 1, 2, 3, and 4 encode the same isoform (1).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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