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Home TrueClone PLK4 Clone

PLK4 (NM_014264) Human Kinase Deficient Mutant

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC323369 PLK4 (untagged)-Kinase deficient mutant (K41M) of Human polo-like kinase 4 (Drosophila) (PLK4) (10ug) NM_014264.2, 10ug $680 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA302688 Goat Polyclonal Antibody against Sak / STK18 / PLK4, 100ug $325 Next Day
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Click here for the corresponding wild type clone.

OriGene Data
Vector:pCMV6-XL5 Insert Size: 3970 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          Kinase domain sequence
OTI Annotation: This kinase-deficient mutant clone was generated by created by site-directed mutagenesis from the corresponding wild-type clone. See details in "Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling." Cell. 2008 May p536-548.
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Protein KinaseDruggable Genome
Reference Data
RefSeq: NM_014264.2, NP_055079
RefSeq Size: 3331 RefSeq ORF: 2913
Synonyms : SAK; STK18
LocusID: 10733 Cytogenetic: 4q28 Domains: pkinase, TyrKc, S_TKc
Summary: This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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