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Home TrueClone IL19 Clone

IL19 (NM_013371) Human cDNA Clone

Specifications Citations (1) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC304003 IL19 (untagged)-Human interleukin 19 (IL19), transcript variant 2 (10ug), NM_013371.2, 10ug $380 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA319096 Rabbit polyclonal anti-IL-19 Polyclonal antibody, 100ug $325 In Stock
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 700 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: This construct is a cloned PCR fragment that was fully sequenced. There are no nucleotide differences between the OriGene clone and the NCBI reference ORF.
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Secreted ProteinDruggable Genome
Protein Pathways: Cytokine-cytokine receptor interactionJak-STAT signaling pathway
Reference Data
RefSeq: NM_013371.2, NP_037503
RefSeq Size: 1831 RefSeq ORF: 534
Synonyms : IL-10C; MDA1; NG.1; ZMDA1
LocusID: 29949 Cytogenetic: 1q32.2
Summary: The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008].

Transcript Variant: This variant (2) lacks an exon from the 5' end and contains two alternate 5' exons, resulting in a downstream AUG start codon, as compared to variant 1. The resulting isoform (2) has a shorter N-terminus, as compared to isoform 1.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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