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Home TrueClone SKP1 Clone

SKP1 (NM_006930) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC126980 SKP1 (untagged)-Human S-phase kinase-associated protein 1 (SKP1), transcript variant 1 (10ug), NM_006930.2, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA307000 Rabbit monoclonal antibody against SKP1 (clone EPR3303 ), 100ul $325 3-7 Days
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 1650 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Druggable Genome
Protein Pathways: Cell cycleOocyte meiosisUbiquitin mediated proteolysisWnt signaling pathwayTGF-beta signaling pathway
Reference Data
RefSeq: NM_006930.2, NP_008861
RefSeq Size: 2172 RefSeq ORF: 483
Synonyms : EMC19; OCP-II; OCP2; p19A; SKP1A; TCEB1L
LocusID: 6500 Cytogenetic: 5q31 Domains: Skp1
Summary: This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008].

Transcript Variant: This variant (1) represents the longer transcript variant but encodes the shorter isoform (a).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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