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Home TrueClone RAC1 Clone

RAC1 (NM_006908) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC124449 RAC1 (untagged)-Human ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) (RAC1), transcript variant Rac1, NM_006908.3, 10ug $190 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA318617 Mouse Anti-Human RAC1 Monoclonal Antibody, 50ug $345 In Stock
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OriGene Data
Vector: pCMV6-XL4 Insert Size: Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Druggable Genome
Protein Pathways: MAPK signaling pathwayChemokine signaling pathwayWnt signaling pathwayAxon guidanceVEGF signaling pathwayFocal adhesionMore Pathways >>
Reference Data
RefSeq Explanation: NM_006908.3, NP_008839
RefSeq Size: 2355 RefSeq ORF: 579
Synonyms : MIG5; p21-Rac1; Rac-1; TC-25
LocusID: 5879 Cytogenetic: 7p22.1 Domains: ras, RAS, RHO, RAB
Gene Summary: Isoform B has an accelerated GEF-independent GDP/GTP exchange and an impaired GTP hydrolysis, which is restored partially by GTPase-activating proteins. It is able to bind to the GTPase-binding domain of PAK but not full-length PAK in a GTP-dependent manner, suggesting that the insertion does not completely abolish effector interaction. [UniProtKB/Swiss-Prot Function]

Transcript Variant: This variant (Rac1) has a 57 bp in-frame deletion of exon 3b in the coding region, as compared to the variant Rac1b.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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