Lipoprotein a (LPA) (NM_005577) Human Untagged Clone

CAT#: SC303668

LPA (untagged)-Human lipoprotein, Lp(a) (LPA)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Lipoprotein a
• Synonyms: AK38; APOA; LP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_005577 edited
  ATGGAACATAAGGAAGTGGTTCTTCTACTTCTTTTATTTCTGAAATCAGCAGCACCTGAG
  CAAAGCCATGTGGTCCAGGATTGCTACCATGGTGATGGACAGAGTTATCGAGGCACGTAC
  TCCACCACTGTCACAGGAAGGACCTGCCAAGCTTGGTCATCTATGACACCACATCAACAT
  AATAGGACCACAGAAAACTACCCAAATGCTGGCTTGATCATGAACTACTGCAGGAATCCA
  GATGCTGTGGCAGCTCCTTATTGTTATACGAGGGATCCCGGTGTCAGGTGGGAGTACTGC
  AACCTGACGCAATGCTCAGACGCAGAAGGGACTGCCGTCGCGCCTCCGACTGTTACCCCG
  GTTCCAAGCCTAGAGGCTCCTTCCGAACAAGCACCGACTGAGCAAAGGCCTGGGGTGCAG
  GAGTGCTACCATGGTAATGGACAGAGTTATCGAGGCACATACTCCACCACTGTCACAGGA
  AGAACCTGCCAAGCTTGGTCATCTATGACACCACACTCGCATAGTCGGACCCCAGAATAC
  TACCCAAATGCTGGCTTGATCATGAACTACTGCAGGAATCCAGATGCTGTGGCAGCTCCT
  TATTGTTATACGAGGGATCCCGGTGTCAGGTGGGAGTACTGCAACCTGACGCAATGCTCA
  GACGCAGAAGGGACTGCCGTCGCGCCTCCGACTGTTACCCCGGTTCCAAGCCTAGAGGCT
  CCTTCCGAACAAGCACCGACTGAGCAAAGGCCTGGGGTGCAGGAGTGCTACCATGGTAAT
  GGACAGAGTTATCGAGGCACATACTCCACCACTGTCACAGGAAGAACCTGCCAAGCTTGG
  TCATCTATGACACCACACTCGCATAGTCGGACCCCAGAATACTACCCAAATGCTGGCTTG
  ATCATGAACTACTGCAGGAATCCAGATGCTGTGGCAGCTCCTTATTGTTATACGAGGGAT
  CCCGGTGTCAGGTGGGAGTACTGCAACCTGACGCAATGCTCAGACGCAGAAGGGACTGCC
  GTCGCGCCTCCGACTGTTACCCCGGTTCCAAGCCTAGAGGCTCCTTCCGAACAAGCACCG
  ACTGAGCAGAGGCCTGGGGTGCAGGAGTGCTACCACGGTAATGGACAGAGTTATCGAGGC
  ACATACTCCACCACTGTCACTGGAAGAACCTGCCAAGCTTGGTCATCTATGACACCACAC
  TCGCATAGTCGGACCCCAGAATACTACCCAAATGCTGGCTTGATCATGAACTACTGCAGG
  AATCCAGATGCTGTGGCAGCTCCTTATTGTTATACGAGGGATCCCGGTGTCAGGTGGGAG
  TACTGCAACCTGACGCAATGCTCAGACGCAGAAGGGACTGCCGTCGCGCCTCCGACTGTT
  ACCCCGGTTCCAAGCCTAGAGGCTCCTTCCGAACAAGCACCGACTGAGCAAAGGCCTGGG
  GTGCAGGAGTGCTACCATGGTAATGGACAGAGTTATCGAGGCACATACTCCACCACTGTC
  ACAGGAAGAACCTGCCAAGCTTGGTCATCTATGACACCACACTCGCATAGTCGGACCCCA
  GAATACTACCCAAATGCTGGCTTGATCATGAACTACTGCAGGAATCCAGATGCTGTGGCA
  GCTCCTTATTGTTATACGAGGGATCCCGGTGTCAGGTGGGAGTACTGCAACCTGACGCAA
  TGCTCAGACGCAGAAGGGACTGCCGTCGCGCCTCCGACTGTTACCCCGGTTCCAAGCCTA
  GAGGCTCCTTCCGAACAAGCACCGACTGAGCAAAGGCCTGGGGTGCAGGAGTGCTACCAT
  GGTAATGGACAGAGTTATCGAGGCACATACTCCACCACTGTCACAGGAAGAACCTGCCAA
  GCTTGGTCATCTATGACACCACACTCGCATAGTCGGACCCCAGAATACTACCCAAATGCT
  GGCTTGATCATGAACTACTGCAGGAATCCAGATGCTGTGGCAGCTCCTTATTGTTATACG
  AGGGATCCCGGTGTCAGGTGGGAGTACTGCAACCTGACGCAATGCTCAGACGCAGAAGGG
  ACTGCCGTCGCGCCTCCGACTGTTACCCCGGTTCCAAGCCTAGAGGCTCCTTCCGAACAA
  GCACCGACTGAGCAAAGGCCTGGGGTGCAGGAGTGCTACCATGGTAATGGACAGAGTTAT
  CGAGGCACATACTCCACCACTGTCACAGGAAGAACCTGCCAAGCTTGGTCATCTATGACA
  CCACACTCGCATAGTCGGACCCCAGAATACTACCCAAATGCTGGCTTGATCATGAACTAC
  TGCAGGAATCCAGATGCTGTGGCAGCTCCTTATTGTTATACGAGGGATCCCGGTGTCAGG
  TGGGAGTACTGCAACCTGACGCAATGCTCAGACGCAGAAGGGACTGCCGTCGCGCCTCCG
  ACTGTTACCCCGGTTCCAAGCCTAGAGGCTCCTTCCGAACAAGCACCGACTGAGCAGAGG
  CCTGGGGTGCAGGAGTGCTACCACGGTAATGGACAGAGTTATCGAGGCACATACTCCACC
  ACTGTCACTGGAAGAACCTGCCAAGCTTGGTCATCTATGACACCACACTCGCATAGTCGG
  ACCCCAGAATACTACCCAAATGCTGGCTTGATCATGAACTACTGCAGGAATCCAGATCCT
  GTGGCAGCCCCTTATTGTTATACGAGGGATCCCAGTGTCAGGTGGGAGTACTGCAACCTG
  ACACAATGCTCAGACGCAGAAGGGACTGCCGTCGCGCCTCCAACTATTACCCCGATTCCA
  AGCCTAGAGGCTCCTTCTGAACAAGCACCAACTGAGCAAAGGCCTGGGGTGCAGGAGTGC
  TACCACGGAAATGGACAGAGTTATCAAGGCACATACTTCATTACTGTCACAGGAAGAACC
  TGCCAAGCTTGGTCATCTATGACACCACACTCGCATAGTCGGACCCCAGCATACTACCCA
  AATGCTGGCTTGATCAAGAACTACTGCCGAAATCCAGATCCTGTGGCAGCCCCTTGGTGT
  TATACAACAGATCCCAGTGTCAGGTGGGAGTACTGCAACCTGACACGATGCTCAGATGCA
  GAATGGACTGCCTTCGTCCCTCCGAATGTTATTCTGGCTCCAAGCCTAGAGGCTTTTTTT
  GAACAAGCACTGACTGAGGAAACCCCCGGGGTACAGGACTGCTACTACCATTATGGACAG
  AGTTACCGAGGCACATACTCCACCACTGTCACAGGAAGAACTTGCCAAGCTTGGTCATCT
  ATGACACCACACCAGCATAGTCGGACCCCAGAAAACTACCCAAATGCTGGCCTGACCAGG
  AACTACTGCAGGAATCCAGATGCTGAGATTCGCCCTTGGTGTTACACCATGGATCCCAGT
  GTCAGGTGGGAGTACTGCAACCTGACACAATGCCTGGTGACAGAATCAAGTGTCCTTGCA
  ACTCTCACGGTGGTCCCAGATCCAAGCACAGAGGCTTCTTCTGAAGAAGCACCAACGGAG
  CAAAGCCCCGGGGTCCAGGATTGCTACCATGGTGATGGACAGAGTTATCGAGGCTCATTC
  TCTACCACTGTCACAGGAAGGACATGTCAGTCTTGGTCCTCTATGACACCACACTGGCAT
  CAGAGGACAACAGAATATTATCCAAATGGTGGCCTGACCAGGAACTACTGCAGGAATCCA
  GATGCTGAGATTAGTCCTTGGTGTTATACCATGGATCCCAATGTCAGATGGGAGTACTGC
  AACCTGACACAATGTCCAGTGACAGAATCAAGTGTCCTTGCGACGTCCACGGCTGTTTCT
  GAACAAGCACCAACGGAGCAAAGCCCCACAGTCCAGGACTGCTACCATGGTGATGGACAG
  AGTTATCGAGGCTCATTCTCCACCACTGTTACAGGAAGGACATGTCAGTCTTGGTCCTCT
  ATGACACCACACTGGCATCAGAGAACCACAGAATACTACCCAAATGGTGGCCTGACCAGG
  AACTACTGCAGGAATCCAGATGCTGAGATTCGCCCTTGGTGTTATACCATGGATCCCAGT
  GTCAGATGGGAGTACTGCAACCTGACGCAATGTCCAGTGATGGAATCAACTCTCCTCACA
  ACTCCCACGGTGGTCCCAGTTCCAAGCACAGAGCTTCCTTCTGAAGAAGCACCAACTGAA
  AACAGCACTGGGGTCCAGGACTGCTACCGAGGTGATGGACAGAGTTATCGAGGCACACTC
  TCCACCACTATCACAGGAAGAACATGTCAGTCTTGGTCGTCTATGACACCACATTGGCAT
  CGGAGGATCCCATTATACTATCCAAATGCTGGCCTGACCAGGAACTACTGCAGGAATCCA
  GATGCTGAGATTCGCCCTTGGTGTTACACCATGGATCCCAGTGTCAGGTGGGAGTACTGC
  AACCTGACACGATGTCCAGTGACAGAATCGAGTGTCCTCACAACTCCCACAGTGGCCCCG
  GTTCCAAGCACAGAGGCTCCTTCTGAACAAGCACCACCTGAGAAAAGCCCTGTGGTCCAG
  GATTGCTACCATGGTGATGGACGGAGTTATCGAGGCATATCCTCCACCACTGTCACAGGA
  AGGACCTGTCAATCTTGGTCATCTATGATACCACACTGGCATCAGAGGACCCCAGAAAAC
  TACCCAAATGCTGGCCTGACCGAGAACTACTGCAGGAATCCAGATTCTGGGAAACAACCC
  TGGTGTTACACAACCGATCCGTGTGTGAGGTGGGAGTACTGCAATCTGACACAATGCTCA
  GAAACAGAATCAGGTGTCCTAGAGACTCCCACTGTTGTTCCAGTTCCAAGCATGGAGGCT
  CATTCTGAAGCAGCACCAACTGAGCAAACCCCTGTGGTCCGGCAGTGCTACCATGGTAAT
  GGCCAGAGTTATCGAGGCACATTCTCCACCACTGTCACAGGAAGGACATGTCAATCTTGG
  TCATCCATGACACCACACCGGCATCAGAGGACCCCAGAAAACTACCCAAATGATGGCCTG
  ACAATGAACTACTGCAGGAATCCAGATGCCGATACAGGCCCTTGGTGTTTTACCATGGAC
  CCCAGCATCAGGTGGGAGTACTGCAACCTGACGCGATGCTCAGACACAGAAGGGACTGTG
  GTCGCTCCTCCGACTGTCATCCAGGTTCCAAGCCTAGGGCCTCCTTCTGAACAAGACTGT
  ATGTTTGGGAATGGGAAAGGATACCGGGGCAAGAAGGCAACCACTGTTACTGGGACGCCA
  TGCCAGGAATGGGCTGCCCAGGAGCCCCATAGACACAGCACGTTCATTCCAGGGACAAAT
  AAATGGGCAGGTCTGGAAAAAAATTACTGCCGTAACCCTGATGGTGACATCAATGGTCCC
  TGGTGCTACACAATGAATCCAAGAAAACTTTTTGACTACTGTGATATCCCTCTCTGTGCA
  TCCTCTTCATTTGATTGTGGGAAGCCTCAAGTGGAGCCGAAGAAATGTCCTGGAAGCATT
  GTAGGGGGGTGTGTGGCCCACCCACATTCCTGGCCCTGGCAAGTCAGTCTCAGAACAAGG
  TTTGGAAAGCACTTCTGTGGAGGCACCTTAATATCCCCAGAGTGGGTGCTGACTGCTGCT
  CACTGCTTGAAGAAGTCCTCAAGGCCTTCATCCTACAAGGTCATCCTGGGTGCACACCAA
  GAAGTGAACCTCGAATCTCATGTTCAGGAAATAGAAGTGTCTAGGCTGTTCTTGGAGCCC
  ACACAAGCAGATATTGCCTTGCTAAAGCTAAGCAGGCCTGCCGTCATCACTGACAAAGTA
  ATGCCAGCTTGTCTGCCATCCCCAGACTACATGGTCACCGCCAGGACTGAATGTTACATC
  ACTGGCTGGGGAGAAACCCAAGGTACCTTTGGGACTGGCCTTCTCAAGGAAGCCCAGCTC
  CTTGTTATTGAGAATGAAGTGTGCAATCACTATAAGTATATTTGTGCTGAGCATTTGGCC
  AGAGGCACTGACAGTTGCCAGGGTGACAGTGGAGGGCCTCTGGTTTGCTTCGAGAAGGAC
  AAATACATTTTACAAGGAGTCACTTCTTGGGGTCTTGGCTGTGCACGCCCCAATAAGCCT
  GGTGTCTATGCTCGTGTTTCAAGGTTTGTTACTTGGATTGAGGGAATGATGAGAAATAAT
  TAA
  
• Restriction Sites: Please inquire
• ACCN: NM_005577
• Insert Size: 6500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005577.1, NP_005568.1
• RefSeq Size: 13938 bp
• RefSeq ORF: 6489 bp
• Locus ID: 4018
• Cytogenetics: 6q25.3-q26
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence. [provided by RefSeq, Dec 2009]