OriGene - AOC3 (NM_003734) cDNA Clone

OriGene Data

Vector:	pCMV6-XL5	Insert Size: 4000	Restriction Site:
Sequence Data:	Fully Sequenced ORF 5' Read Nucleotide Sequence
OTI Annotation:	The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
OTI Disclaimer:	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components:	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families:	Transmembrane
Protein Pathways:	Glycine, serine and threonine metabolism Tyrosine metabolism Phenylalanine metabolism beta-Alanine metabolism Metabolic pathways

Reference Data

RefSeq: NM_003734.2, NP_003725	RefSeq Size: 4040	RefSeq ORF: 2292
Synonyms : HPAO; SSAO; VAP-1; VAP1
LocusID: 8639	Cytogenetic: 17q21
Summary: Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb downstream. [provided by RefSeq, Jul

TrueClone Citations:

MPN patients harbor recurrent truncating mutations in transcription factor NF-E2, Jonas S. Jutzi, Ruzhica Bogeska, Gorica Nikoloski, Corina A. Schmid, Thalia S. Seeger, Frank Stegelmann, Sven Schwemmers, Albert Gründer, Jan C. Peeken, Monika Gothwal, Julius Wehrle, Konrad Aumann, Kamar Hamdi, Christine Dierks, Wei Wang, Konstanze Döhner, Joop H. Jansen, and Heike L. Pahl, J. Exp. Med., May 2013; 210: 1003 - 1019. [MAFG]

The Human Tim-Tipin Complex Interacts Directly with DNA Polymerase and Stimulates Its Synthetic Activity, Valentina Aria, Mariarita De Felice, Roberta Di Perna, Shuji Uno, Hisao Masai, Juhani E. Syväoja, Barbara van Loon, Ulrich Hübscher, and Francesca M. Pisani, J. Biol. Chem., May 2013; 288: 12742 - 12752. [TIPIN]

Reciprocal Regulation of Protein Kinase and Pyruvate Kinase Activities of Pyruvate Kinase M2 by Growth Signals, Xueliang Gao, Haizhen Wang, Jenny J. Yang, Jing Chen, Jiang Jie, Liangwei Li, Yinwei Zhang, and Zhi-Ren Liu, J. Biol. Chem., May 2013; 288: 15971 - 15979. [PKM2]

Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors a- and -mediated transactivation, Yukimasa Takeda and Anton M. Jetten, Nucleic Acids Res., May 2013; 10.1093/nar/gkt447. [Prox1 ]

Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia, Hanna L. M. Rajala, Samuli Eldfors, Heikki Kuusanmäki, Arjan J. van Adrichem, Thomas Olson, Sonja Lagström, Emma I. Andersson, Andres Jerez, Michael J. Clemente, Yiyi Yan, Dan Zhang, Andy Awwad, Pekka Ellonen, Olli Kallioniemi, Krister Wennerberg, Kimmo Porkka, Jaroslaw P. Maciejewski, Thomas P. Loughran, Jr, Caroline Heckman, and Satu Mustjoki, Blood, May 2013; 121: 4541 - 4550. [STAT5B]

Expression of recombinant human complement C1q allows identification of the C1r/C1s-binding sites, Isabelle Bally, Sarah Ancelet, Christine Moriscot, Florence Gonnet, Alberto Mantovani, Régis Daniel, Guy Schoehn, Gérard J. Arlaud, and Nicole M. Thielens, PNAS, May 2013; 110: 8650 - 8655. [C1qA]

MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension, Ryan S. Friese, Angelina E. Altshuler, Kuixing Zhang, Jose Pablo Miramontes-Gonzalez, C. Makena Hightower, Martin L. Jirout, Rany M. Salem, Jiaur R. Gayen, Nitish R. Mahapatra, Nilima Biswas, Mo Cale, Sucheta M. Vaingankar, Hyung-Suk Kim, Maïté Courel, Laurent Taupenot, Michael G. Ziegler, Nicholas J. Schork, Michal Pravenec, Sushil K. Mahata, Geert W. Schmid-Schönbein, and Daniel T. O'Connor, Hum. Mol. Genet., May 2013; 10.1093/hmg/ddt213. [HAND1]

Development of LC/MS/MS, High-Throughput Enzymatic and Cellular Assays for the Characterization of Compounds That Inhibit Kynurenine Monooxygenase (KMO), Dirk Winkler, Maria Beconi, Leticia M. Toledo-Sherman, Michael Prime, Andreas Ebneth, Celia Dominguez, and Ignacio Muñoz-Sanjuan, J Biomol Screen, May 2013; 10.1177/1087057113489731. [KMO]

More TrueClone Citations >>

AOC3 Mouse Clones

SKU	Description	Amount	Price	Shipping
MC221415	Mus musculus amine oxidase, copper containing 3 (Aoc3) as transfection-ready DNA	10 ug	$920	3 weeks
MR209593	Myc-DDK-tagged ORF clone of Mus musculus amine oxidase, copper containing 3 (Aoc3) as transfection-ready DNA	10 ug	$920	Next day
MG209593	GFP-tagged ORF clone of Mus musculus amine oxidase, copper containing 3 (cDNA clone MGC:90714 IMAGE:6854465) in a GFP expression vector	10 ug	$1010	3 weeks

AOC3 Rat Clones

SKU	Description	Amount	Price	Shipping
RN207330	NativeORF clone of Rattus norvegicus amine oxidase, copper containing 3 (vascular adhesion protein 1) (Aoc3) as transfection-ready DNA	10 ug	$917	6 weeks
RR207330	Myc-DDK-tagged ORF clone of Rattus norvegicus amine oxidase, copper containing 3 (vascular adhesion protein 1) (Aoc3) as transfection-ready DNA	10 ug	$917	6 weeks

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AOC3 (NM_003734) Human cDNA Clone

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AOC3 Mouse Clones

AOC3 Rat Clones

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