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Home TrueClone FLT1 Clone

FLT1 (NM_002019) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC118893 FLT1 (untagged)-Human fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (FLT1), transcript variant 1 (10ug), NM_002019.2, 10ug $2410 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA313883 Rabbit polyclonal anti-VEGFR1 antibody, 100ul $325 3 Weeks
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Click here for the corresponding kinase deficient mutant clone.
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Also for FLT1 (NM_002019)
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 7000 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: A TrueClone.
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Protein KinaseSecreted ProteinDruggable Genome
Protein Pathways: Cytokine-cytokine receptor interactionEndocytosisFocal adhesion
Reference Data
RefSeq: NM_002019.2, NP_002010
RefSeq Size: 5777 RefSeq ORF: 4017
Synonyms : FLT; FLT-1; VEGFR-1; VEGFR1
LocusID: 2321 Cytogenetic: 13q12 Domains: pkinase, TyrKc, S_TKc, ig, IGv, IGc2, IG
Summary: This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009].

Transcript Variant: This variant (1) the longest isoform (1). Isoform 1 is a transmembrane protein.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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