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Home TrueClone GABBR1 Clone

GABBR1 (NM_001470) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC109253 GABBR1 (untagged)-Human gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1), transcript variant 1 (10ug), NM_001470.1, 10ug $1730 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA313902 Rabbit polyclonal anti-GABBR1 antibody, 100ul $325 3 Weeks
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 5130 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: GPCRSecreted ProteinTransmembraneDruggable Genome
Protein Pathways: Neuroactive ligand-receptor interaction
Reference Data
RefSeq: NM_001470.1, NP_001461
RefSeq Size: 4445 RefSeq ORF: 2886
Synonyms : dJ271M21.1.1; dJ271M21.1.2; GABABR1; GABBR1-3; GB1; GPRC3A
LocusID: 2550 Cytogenetic: 6p21.31 Domains: 7tm_3, CCP, ANF_receptor
Summary: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].

Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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