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Home TrueClone IL6 Clone

IL6 (NM_000600) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC125236 IL6 (untagged)-Human interleukin 6 (interferon, beta 2) (IL6) (10ug), NM_000600.1, 10ug $380 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA300413 Rabbit Monoclonal Antibody against IL6 (Clone E457), 100ul $325 In Stock
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 800 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Secreted ProteinDruggable Genome
Protein Pathways: Cytokine-cytokine receptor interactionToll-like receptor signaling pathwayNOD-like receptor signaling pathwayCytosolic DNA-sensing pathwayJak-STAT signaling pathwayHematopoietic cell lineageMore Pathways >>
Reference Data
RefSeq: NM_000600.1, NP_000591
RefSeq Size: 1125 RefSeq ORF: 639
Synonyms : BSF2; HGF; HSF; IFNB2; IL-6
LocusID: 3569 Cytogenetic: 7p21
Summary: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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