Dr.H Varmus's lab used TissueScan in a recent publication in Oncogene (2009) MYC-induced myeloid leukemogenesis is accelerated by all six members of the antiapoptotic BCL family

"Using TissueScan oncology survey panel from Origene, we performed quantitative real-time PCR analysis on cDNA acquired from 60 different tissues and tumor samples. Following quantitative real-time PCR analysis, we observed elevated levels of BFL1 in eight of nine breast tumor samples and three of nine colon tumor samples, compared to the normal tissue controls. Increased BCL2 expression was also detected in seven of the nine breast cancer samples, and BCLxl was overexpressed in a number of ovarian tumors."

Akt2 overexpression plays a critical role in the establishment of colorectal cancer metastasis, PNAS, Dec 2008; 105: 20315 - 20320. (Colon Cancer panel)

Interplay between the Nuclear Receptor Pregnane X Receptor and the Uptake Transporter Organic Anion Transporter Polypeptide 1A2 Selectively Enhances Estrogen Effects in Breast Cancer, Cancer Res., Nov 2008; 68: 9338 - 9347. (Breast Cancer Panels)
EBP1, an ErbB3-binding protein, is decreased in prostate cancer and implicated in hormone resistance, Mol. Cancer Ther., Oct 2008; 7: 3176 - 3186 (Prostate Cancer Panel)

Gene Expression Introduction

Gene expression image qPCR products for gene expression analysis are a critical part of OriGene’s “gene-centric” product strategy. We provide unique reagents and tools for real-time qPCR, cancer tissue qPCR arrays for biomarker discovery and validation.

TissueScan Cancer qPCR arrays

Gene specific expression profiling across many cancer tissues
Ideal for biomarker discovery and validation
40 different qPCR arrays covering 14 different cancer types, as well as normal tissues

qPCR Reagents

SybGREEN qPCR Primer Pairs

Technical Support
Our scientists will answer your technical questions from 9AM to 7PM ET. Call 1-888-267-4436
- Pre-designed and validated primers for all human and mouse genes
- SYBR Green qPCR experiments
Gene specific qPCR Template Standards
- Unique offering as qPCR assay controls
- Determine transcript copy numbers.
- >14,000 gene specific standards

First Strand cDNA

High quality first strand cDNA for gene expression anaylsis
Broad selection from human, mouse and rat normal tissues

Rapid-Scan cDNA Panels

Panels of pre-normalized, serial diluted cDNAs derived from various tissues and/or developmental stages from human, mouse or Drosophila. A simple PCR reaction with gene-specific primers followed by an agarose gel would generate comprehensive expression profiles of any cloned gene or EST.