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Home TrueClone WFDC2 Clone

WFDC2 (NM_080734) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC305822 WFDC2 (untagged)-Human WAP four-disulfide core domain 2 (WFDC2), transcript variant 4 (10ug), NM_080734.1, 10ug $580 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA307787 Rabbit monoclonal antibody against HE4(clone EPR4743), 100ul $325 In Stock
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 520 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Secreted ProteinTransmembrane
Reference Data
RefSeq: NM_080734.1, NP_542772
RefSeq Size: 421 RefSeq ORF: 231
Synonyms : HE4, WAP5, MGC57529, dJ461P17.6
LocusID: 10406 Cytogenetic: 20q13.12
Summary: This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008].

Transcript Variant: This variant (4) lacks a fragment within the coding region, as compared to variant 1. Its reading frame is not impacted by the absence of the fragment, and it thus encodes a smaller protein which has identical N- and C-terminus to those of isoform 1 and contains only one WFDC domain.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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