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Home TrueClone KIRREL2 Clone

KIRREL2 (NM_032123) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC305401 KIRREL2 (untagged)-Human kin of IRRE like 2 (Drosophila) (KIRREL2), transcript variant 1, NM_032123.6, 10ug $980 3 weeks
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TT200002 MegaTran 1.0 (0.5ml), 165 rxns for 24-well plates, 0.5ml $90 In Stock
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Also for KIRREL2 (NM_032123)
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OriGene Data
Vector: pCMV6-Entry QM Insert Size: Restriction Site: SgfI-MluI
Sequence Data: Fully Sequenced ORF         
OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Transmembrane
Reference Data
RefSeq Explanation: NM_032123.6, NP_115499
RefSeq Size: 2582 RefSeq ORF: 1902
Synonyms : FILTRIN; NEPH3; NLG1
LocusID: 84063 Cytogenetic: 19q13.12
Gene Summary: This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter. [provided by RefSeq, Jul 2016].

Transcript Variant: This variant (1) differs in the 5' UTR and contains an alternate intron in the 3' coding region, which results in a frameshift compared to variant 3. The encoded isoform (a) is shorter and has a distinct C-terminus compared to isoform c.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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