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Home TrueClone MARCH2 Clone

MARCH2 (NM_016496) Human cDNA Clone

Specifications Citations (1) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC114251 41335 (untagged)-Human membrane-associated ring finger (C3HC4) 2 (MARCH2), transcript variant 1 (10ug), NM_016496.3, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA315456 Rabbit polyclonal anti-MARCH2 antibody, 100ul $325 In Stock
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Also for MARCH2 (NM_016496)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data
Vector:pCMV6-XL5 Insert Size: 1250 Restriction Site: ECoRI-NOT
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: TransmembraneDruggable Genome
Reference Data
RefSeq: NM_016496.3, NP_057580
RefSeq Size: 1745 RefSeq ORF: 741
Synonyms : HSPC240; MARCH-II; RNF172
LocusID: 51257 Cytogenetic: 19p13.2 Domains: zf-C3HC4
Summary: MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM, Mar 2010].

Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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