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Home TrueClone LEF1 Clone

LEF1 (NM_016269) Human cDNA Clone

Specifications Citations (1) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC114370 LEF1 (untagged)-Human lymphoid enhancer-binding factor 1 (LEF1), transcript variant 1 (10ug), NM_016269.2, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA307089 Rabbit monoclonal antibody against LEF-1/TCF-1 alpha (clone EP2030Y ), 100ul $325 In Stock
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 2660 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: ES Cell Differentiation/IPSAdult stem cellsTranscription FactorsDruggable Genome
Protein Pathways: Wnt signaling pathwayAdherens junctionMelanogenesisPathways in cancerColorectal cancerEndometrial cancerMore Pathways >>
Reference Data
RefSeq: NM_016269.2, NP_057353
RefSeq Size: 3084 RefSeq ORF: 1200
Synonyms : LEF-1; TCF10; TCF1ALPHA; TCF7L3
LocusID: 51176 Cytogenetic: 4q23 Domains: HMG
Summary: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].

Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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