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Home TrueClone PTK2 Clone

PTK2 (NM_005607) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC326330 PTK2 (untagged)-Human PTK2 protein tyrosine kinase 2 (PTK2), transcript variant 2 (10ug), NM_005607.3, 10ug $1940 3 weeks
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA300620 Rabbit Monoclonal Antibody against PTK2 (Clone EP695Y), 100ul $325 3-7 Days
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OriGene Data
Vector:pCMV6 Entry Insert Size: Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Protein KinaseDruggable Genome
Protein Pathways: ErbB signaling pathwayChemokine signaling pathwayAxon guidanceVEGF signaling pathwayFocal adhesionLeukocyte transendothelial migrationMore Pathways >>
Reference Data
RefSeq: NM_005607.3, NP_005598
RefSeq Size: RefSeq ORF: 3224
Synonyms : FADK; FAK; FAK1; FRNK; p125FAK; pp125FAK; PPP1R71
LocusID: 5747 Cytogenetic: 8q24.3 Domains: B41, pkinase, TyrKc, S_TKc, Focal_AT
Summary: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010].

Transcript Variant: This variant (2) encodes the longest isoform (b).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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