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 Home TrueClone CDK2 Clone

CDK2 (NM_001798) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC109059 ORIGENE UNIQUE VARIANT 1 of Homo sapiens cyclin-dependent kinase 2 (CDK2), as transfection-ready DNA NM_001798.2, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA502936 Purified CDK2 mouse monoclonal antibody, clone 6H2, 100ul $325 In Stock
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Click here for the corresponding kinase deficient mutant clone.
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 3370 Restriction Site: NotI-NotI
Sequence Data: 5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Annotation: This TrueClone was found to represent an alternative form of the specific reference to which it is associated. Its Open Reading Frame (ORF) may represent a novel form or alternative splice variant. By virtue of it being a true transcript (cDNA clone not PCR product), it provides a biologically relevant copy of its mRNA template. For more details, please evaluate the sequence information provided on this website or contact our customer care specialists.
OTI Disclaimer: The sequence of an 'OriGene Unique Variant' differs significantly from the associated reference. It represents a novel splice variant from the same gene locus of the reference. Although such variants are true transcripts and present opportunity for discoveries, they are not yet curated by NCBI and should not be used if the exact reference accession sequence is required.
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Protein KinaseDruggable Genome
Protein Pathways: Cell cycleOocyte meiosisp53 signaling pathwayProgesterone-mediated oocyte maturationPathways in cancerProstate cancerMore Pathways >>
Reference Data
RefSeq: NM_001798.2, NP_001789
 RefSeq Size: 2328 RefSeq ORF: 897
Synonyms : p33(CDK2)
LocusID: 1017 Cytogenetic: 12q13 Domains: pkinase, TyrKc, S_TKc
Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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