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Home TrueClone KLK6 Clone

KLK6 (NM_001012964) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC322327 KLK6 (untagged)-Human kallikrein-related peptidase 6 (KLK6), transcript variant B (10ug), NM_001012964.1, 10ug $380 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA309722 Rabbit Polyclonal Kallikrein 6 Antibody, 0.1ml $325 3-7 Days
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OriGene Data
Vector:pCMV6-AC Insert Size: Restriction Site: RsrII-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Secreted ProteinProteaseDruggable Genome
Reference Data
RefSeq: NM_001012964.1, NP_001012982
RefSeq Size: 1527 RefSeq ORF: 734
Synonyms : Bssp; hK6; Klk7; PRSS18; PRSS9; SP59
LocusID: 5653 Cytogenetic: 19q13.3
Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].

Transcript Variant: This variant (B), also called transcript variant 1, differs in the 5' UTR compared to variant A. Variants A and B encode the same isoform (A). Multiple transcriptional start sites exist for variant B.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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