Bat3 promotes the membrane integration of tail-anchored proteins J. Cell Sci., Jul 2010; 123: 2170 - 2178 [BAT3]

Caveolin-1 modulates HIV-1 envelope induced bystander apoptosis through gp41 J. Virol., Jul 2010; 84: 6515 - 6526 [CAV1]

Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression PNAS, Jul 2010; 107: 12210 - 12215 [PXDN]

HIV infection upregulates Caveolin 1 (Cav-1) expression to restrict virus production J. Virol., Jul 2010; 10.1128/JVI.00763-10. [CAV1]

IGF1R (NM_000875) Human cDNA Clone

Specifications

Related Products

Product Manual

FAQs

Cat. No.

Ref. ID

Description

Amount

Price

Shipping

SC114570

NM_000875

ORIGENE UNIQUE VARIANT 1 of Homo sapiens insulin-like growth factor 1 receptor (IGF1R) as transfection-ready DNA NM_000875.2

$1000

Next day

Also for IGF1R (NM_000875)

OriGene TrueClone Data

Vector:	pCMV6-XL4	Insert Size: 4760	Restriction Site: NotI-NotI
Sequence Data:	5' Read Nucleotide Sequence 3' Read Nucleotide Sequence
OTI Annotation:	This TrueClone was found to represent an alternative form of the specific reference to which it is associated. Its Open Reading Frame (ORF) may represent a novel form or alternative splice variant. By virtue of it being a true transcript (cDNA clone not PCR product), it provides a biologically relevant copy of its mRNA template. For more details, please evaluate the sequence information provided on this website or contact our customer care specialists.
OTI Disclaimer:	The sequence of an 'OriGene Unique Variant' differs significantly from the associated reference. It represents a novel splice variant from the same gene locus of the reference. Although such variants are true transcripts and present opportunity for discoveries, they are not yet curated by NCBI and should not be used if the exact reference accession sequence is required.
Product Components:	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.

Reference Data

RefSeq: NM_000875.2, NP_000866	RefSeq Size: 4989	RefSeq ORF: 4104
Synonyms : CD221; IGFIR; IGFR; JTK13; MGC142170; MGC142172; MGC18216
LocusID: 3480	Cytogenetic: 15q26.3
Summary: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq].