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Home TrueClone CHRNA4 Clone

CHRNA4 (NM_000744) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC300129 CHRNA4 (untagged)-Human cholinergic receptor, nicotinic, alpha 4 (CHRNA4) (10ug), NM_000744.2, 10ug $680 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA310330 Rabbit Monoclonal antibody against ACHR-alpha 4 (CHRNA4), 100ul $325 3-7 Days
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Also for CHRNA4 (NM_000744)
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 2100 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Annotation: This RT-PCR clone has 4 nucleotide differences from the NCBI reference ORF. These result in the substitution of no amino acids. While there is a new version, NM_000744.3, the ORF has not changed between versions.
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Ion Channels: Cys-loop ReceptorsTransmembraneDruggable Genome
Reference Data
RefSeq: NM_000744.2, NP_000735
RefSeq Size: 3773 RefSeq ORF: 1884
Synonyms : BFNC; EBN; EBN1; NACHR; NACHRA4; NACRA4
LocusID: 1137 Cytogenetic: 20q13.33
Summary: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb

Transcript Variant: This variant (1) encodes the longer isoform (1).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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