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ADRA2C (NM_000683) Human cDNA Clone

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SC124091

NM_000683

Homo sapiens adrenergic, alpha-2C-, receptor (ADRA2C) as transfection-ready DNA NM_000683.3

$480

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Also for ADRA2C (NM_000683)

OriGene TrueClone Data

Vector:	pCMV6-XL4	Insert Size: 2000	Restriction Site:
Sequence Data:	5' Read Nucleotide Sequence 3' Read Nucleotide Sequence
OTI Disclaimer:	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components:	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.

Reference Data

RefSeq: NM_000683.3, NP_000674	RefSeq Size: 1958	RefSeq ORF: 1389
Synonyms : ADRA2L2; ADRA2RL2; ADRARL2; ALPHA2CAR
LocusID: 152	Cytogenetic: 4p16
Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq].