OriGene cDNAs in recent publications

BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression, Mol. Cell. Biol. Nov.2008; 28(21): p. 6720-6729 [BAT3]

Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1, Circ. Res., Oct 2008; 10.1161/01.RES.0000338597.71702.ad. [AKT1]

Interactions of S100A2 and S100A6 with the Tetratricopeptide Repeat Proteins, Hsp90/Hsp70-organizing Protein and Kinesin Light Chain, J. Biol. Chem., Oct 2008; 283: 28246 - 28258. [TOR1A]

Significance of Organic Cation Transporter 3 (SLC22A3) Expression for the Cytotoxic Effect of Oxaliplatin in Colorectal Cancer, Drug Metab. Dispos., Nov 2008; 36: 2299 - 2306. [POU5F1(OCT3)]

Stroma-dependent apoptosis in clonal hematopoietic precursors correlates with expression of PYCARD Blood, Oct 2008; 10.1182/blood-2008-04-152686. [TNFRSF1A]

TRUECLONE COLLECTION

Cat. No.	Ref. ID	Description	Delivery
SC119843	NM_000459	Homo sapiens TEK tyrosine kinase, endothelial (TEK) as transfection-ready DNA NM_000459.1	Immediate
		The use of this clone has been cited in the linked publication
Larger aliquots of this purified plasmid are available on the next page. For 50 ug and 100 ug orders, delivery will take four additional weeks from the estimated delivery time.

Researchers who bought this clone have also purchased:

Related Lysate from OriGene

•	Antigen standard for TEK (NM_000459) (transient overexpression lysate)

RNA Interference Products

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shRNA Constructs against Mus musculus Tek in pGFP-V-RS Vector

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HuSH 29mer shRNA Constructs against TEK

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shRNA Constructs against Mus musculus Tek

Related cDNA Clones from OriGene

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Homo sapiens TEK tyrosine kinase, endothelial (TEK) as transfection-ready DNA

Related ORF Clones from OriGene

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ORF Clone of Homo sapiens TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal) (TEK) as transfection-ready DNA

Cloning Vectors

•	PrecisionShuttle - shuttle vectors for TrueORF
•	pCMV expression vector - for use as a negative control
•	pCMV NEOr vector - for stable cell line generation

Gene Expression Products

•	TissueScan Tissue qPCR Arrays
•	OriGene RapidScan Gene Expression Panels

Western Blotting Reagents

•	MYC/DDK Tagged Western Blot Molecular Weight Markers
•	Anti-tag antibodies
•	HRP-Conjugated secondary antibodies and Western blot reagents

Validated Antibodies

•	Purified TEK (C-term ) Rabbit Polyclonal Antibody

Reference Data

Family: Kinase	RefSeq Size: 4138	RefSeq ORF: 3375
RefSeq: NM_000459.1, NP_000450 LocusID: 7010 Cytogenetic: 9p21 Domains: pkinase, TyrKc, S_TKc, FN3, EGF, EGF Summary: The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq].