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 Home TrueClone L1CAM Clone

L1CAM (NM_000425) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC109376 Homo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 1 as transfection-ready DNA NM_000425.2, 10ug $980 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA500729 L1CAM mouse monoclonal antibody, clone 2C7, 100ul $325 In Stock
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 5000 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Annotation: A TrueClone.
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: ES Cell Differentiation/IPSTransmembraneDruggable Genome
Protein Pathways: Axon guidanceCell adhesion molecules (CAMs)
Reference Data
RefSeq: NM_000425.2, NP_000416
 RefSeq Size: 4525 RefSeq ORF: 3774
Synonyms : CAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1
LocusID: 3897 Cytogenetic: Xq28 Domains: ig, IGc2, IG, FN3
Summary: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq, Jul 2008].

Transcript Variant: This variant (1) includes a neuron-specific exon in the 3' region and encodes the full-length isoform (1).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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