OriGene cDNAs in recent publications

BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression, Mol. Cell. Biol. Nov.2008; 28(21): p. 6720-6729 [BAT3]

Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1, Circ. Res., Oct 2008; 10.1161/01.RES.0000338597.71702.ad. [AKT1]

Interactions of S100A2 and S100A6 with the Tetratricopeptide Repeat Proteins, Hsp90/Hsp70-organizing Protein and Kinesin Light Chain, J. Biol. Chem., Oct 2008; 283: 28246 - 28258. [TOR1A]

Significance of Organic Cation Transporter 3 (SLC22A3) Expression for the Cytotoxic Effect of Oxaliplatin in Colorectal Cancer, Drug Metab. Dispos., Nov 2008; 36: 2299 - 2306. [POU5F1(OCT3)]

Stroma-dependent apoptosis in clonal hematopoietic precursors correlates with expression of PYCARD Blood, Oct 2008; 10.1182/blood-2008-04-152686. [TNFRSF1A]

TRUECLONE COLLECTION

Cat. No.	Ref. ID	Description	Delivery
SC125449	NM_000215	ORIGENE UNIQUE VARIANT 1 of Homo sapiens Janus kinase 3 (a protein tyrosine kinase, leukocyte) (JAK3) as transfection-ready DNA NM_000215.2	3-5 weeks

Larger aliquots of this purified plasmid are available on the next page. For 50 ug and 100 ug orders, delivery will take four additional weeks from the estimated delivery time.

Researchers who bought this clone have also purchased:

Related Lysate from OriGene

•	Antigen standard for JAK3 (NM_000215) (transient overexpression lysate)
•	Antigen standard for JAK3 (NM_000215) (transient overexpression lysate)

RNA Interference Products

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shRNA Constructs against Mus musculus Jak3 in pGFP-V-RS Vector

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HuSH 29mer shRNA Constructs against JAK3

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shRNA Constructs against Mus musculus Jak3

Related cDNA Clones from OriGene

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ORIGENE UNIQUE VARIANT 1 of Homo sapiens Janus kinase 3 (a protein tyrosine kinase, leukocyte) (JAK3) as transfection-ready DNA

•

Homo sapiens Janus kinase 3 (a protein tyrosine kinase, leukocyte) (JAK3) as transfection-ready DNA

Related ORF Clones from OriGene

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ORF Clone of Homo sapiens Janus kinase 3 (a protein tyrosine kinase, leukocyte) (JAK3) as transfection-ready DNA

Cloning Vectors

•	PrecisionShuttle - shuttle vectors for TrueORF
•	pCMV expression vector - for use as a negative control
•	pCMV NEOr vector - for stable cell line generation

Gene Expression Products

•	TissueScan Tissue qPCR Arrays
•	OriGene RapidScan Gene Expression Panels

Western Blotting Reagents

•	MYC/DDK Tagged Western Blot Molecular Weight Markers
•	Anti-tag antibodies
•	HRP-Conjugated secondary antibodies and Western blot reagents

Reference Data

Family: Kinase	RefSeq Size: 4025	RefSeq ORF: 3375
RefSeq: NM_000215.2, NP_000206 LocusID: 3718 Cytogenetic: 19p13.1 Domains: B41, pkinase, SH2, TyrKc, S_TKc Summary: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq].