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Home TrueClone DLD Clone

DLD (NM_000108) Human cDNA Clone

Specifications Citations (1) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC126940 DLD (untagged)-Human dihydrolipoamide dehydrogenase (DLD) (10ug), NM_000108.2, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA503422 DLD (Lipoamide Dehydrogenase) mouse monoclonal antibody, clone 4A10, 100ul $325 In Stock
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 2190 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Druggable Genome
Protein Pathways: Glycolysis / GluconeogenesisCitrate cycle (TCA cycle)Glycine, serine and threonine metabolismValine, leucine and isoleucine degradationPyruvate metabolismMetabolic pathways
Reference Data
RefSeq: NM_000108.2, NP_000099
RefSeq Size: 2320 RefSeq ORF: 1530
Synonyms : DLDD; DLDH; E3; GCSL; LAD; PHE3
LocusID: 1738 Cytogenetic: 7q31 Domains: pyr_redox, pyr_redox_dim
Summary: This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].

Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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