OriGene - BCL2L12 (BC007724) cDNA Clone

OriGene Data

Vector:	pCMV6-XL5	Insert Size: 1037	Restriction Site:
Sequence Data:	Fully Sequenced ORF 5' Read Nucleotide Sequence
OTI Disclaimer:	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components:	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families:	Druggable Genome
Protein Pathways:

Reference Data

RefSeq: BC007724.1, AAH07724	RefSeq Size: 1037	RefSeq ORF: 753
Synonyms : MGC120313; MGC120314; MGC120315; BCL2-like 12; Bcl-2 related proline-rich protein; BCL2-like 12 (proline rich)
LocusID: 83596	Cytogenetic: 19q13.3
Summary: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 2 (BH2). The function of this gene has not yet been determined. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

TrueClone Citations:

Dihydrotestosterone and Bicalutamide Do Not Affect Periostin Expression in Androgen-dependent LNCaP Prostate Cancer Cell Lines, FRANCESCA ARGELLATI, PIER VITALE NUZZO, FRANCESCO RICCI, ROSA MANGERINI, ALESSANDRA RUBAGOTTI, and FRANCESCO BOCCARDO, Anticancer Res, Mar 2013; 33: 815 - 820. [POSTN]

An SRF/miR-1 axis regulates NCX1 and Annexin A5 protein levels in the normal and failing heart, Eva Tritsch, Youssef Mallat, Florence Lefebvre, Nicolas Diguet, Brigitte Escoubet, Jocelyne Blanc, Leon J. De Windt, Daniele Catalucci, Grégoire Vandecasteele, Zhenlin Li, and Mathias Mericskay, Cardiovasc Res, Mar 2013; 10.1093/cvr/cvt042. [JunD]

CSF1R mutations link POLD and HDLS as a single disease entity, Alexandra M. Nicholson, Matt C. Baker, NiCole A. Finch, Nicola J. Rutherford, Christian Wider, Neill R. Graff-Radford, Peter T. Nelson, H. Brent Clark, Zbigniew K. Wszolek, Dennis W. Dickson, David S. Knopman, and Rosa Rademakers, Neurology, Mar 2013; 80: 1033 - 1040. [CSF1R ]

Induced CYP3A4 Expression in Confluent Huh7 Hepatoma Cells as a Result of Decreased Cell Proliferation and Subsequent Pregnane X Receptor Activation, Louise Sivertsson, Irene Edebert, Margareta Porsmyr Palmertz, Magnus Ingelman-Sundberg, and Etienne P. A. Neve, Mol. Pharmacol., Mar 2013; 83: 659 - 670. [NR1I2 ]

The Mediator complex subunit MED25 is targeted by the N-terminal transactivation domain of the PEA3 group members, Alexis Verger, Jean-Luc Baert, Kathye Verreman, Frédérique Dewitte, Elisabeth Ferreira, Zoé Lens, Yvan de Launoit, Vincent Villeret, and Didier Monté, Nucleic Acids Res., Mar 2013; 10.1093/nar/gkt199. [MED25]

Centaurin-a1-Ras-Elk-1 Signaling at Mitochondria Mediates ß-Amyloid-Induced Synaptic Dysfunction, Erzsebet M. Szatmari, Ana F. Oliveira, Elizabeth J. Sumner, and Ryohei Yasuda, J. Neurosci., Mar 2013; 33: 5367 - 5374. [APP]

Activation of the Ca2+-sensing receptor increases renal claudin-14 expression and urinary Ca2+ excretion, Henrik Dimke, Prajakta Desai, Jelena Borovac, Alyssa Lau, Wanling Pan, and R. Todd Alexander, Am J Physiol Renal Physiol, Mar 2013; 304: F761 - F769. [Cldn14]

Mechanisms by which the orexigen NPY regulates anorexigenic a-MSH and TRH, Nicole E. Cyr, Anika M. Toorie, Jennifer S. Steger, Matthew M. Sochat, Samantha Hyner, Mario Perello, Ronald Stuart, and Eduardo A. Nillni, Am J Physiol Endocrinol Metab, Mar 2013; 304: E640 - E650. [NYP1R]

Involvement of Lyn and the Atypical Kinase SgK269/PEAK1 in a Basal Breast Cancer Signaling Pathway, David R. Croucher, Falko Hochgräfe, Luxi Zhang, Ling Liu, Ruth J. Lyons, Danny Rickwood, Carole M. Tactacan, Brigid C. Browne, Naveid Ali, Howard Chan, Robert Shearer, David Gallego-Ortega, Darren N. Saunders, Alexander Swarbrick, and Roger J. Daly, Cancer Res., Mar 2013; 73: 1969 - 1980. [SGK269 ]

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BCL2L12 Mouse Clones

SKU	Description	Amount	Price	Shipping
MC206958	Mus musculus BCL2-like 12 (proline rich) (cDNA clone MGC:48217 IMAGE:1529147) as transfection-ready DNA	10 ug	$300	2 weeks
MC211688	Mus musculus BCL2-like 12 (proline rich) (Bcl2l12) as transfection-ready DNA	10 ug	$380	4 weeks
MR201753	Myc-DDK-tagged ORF clone of Mus musculus BCL2-like 12 (proline rich) (cDNA clone MGC:48217 IMAGE:1529147) as transfection-ready DNA	10 ug	$300	Next day
MR226674	Myc-DDK-tagged ORF clone of Mus musculus BCL2-like 12 (proline rich) (Bcl2l12) as transfection-ready DNA	10 ug	$380	4 weeks
MG201753	GFP-tagged ORF clone of Mus musculus BCL2-like 12 (proline rich) (cDNA clone MGC:48217 IMAGE:1529147) in a GFP expression vector	10 ug	$330	Next day
MG226674	GFP-tagged ORF clone of Mus musculus BCL2-like 12 (proline rich) (Bcl2l12) as transfection-ready DNA	10 ug	$420	3 weeks

BCL2L12 Rat Clones

SKU	Description	Amount	Price	Shipping
RN212858	NativeORF clone of Rattus norvegicus BCL2-like 12 (proline rich) (Bcl2l12) as transfection-ready DNA	10 ug	$380	4 weeks
RR212858	Myc-DDK-tagged ORF clone of Rattus norvegicus BCL2-like 12 (proline rich) (Bcl2l12) as transfection-ready DNA	10 ug	$380	4 weeks

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BCL2L12 (BC007724) Human cDNA Clone

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BCL2L12 Mouse Clones

BCL2L12 Rat Clones

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