Serine racemase (SRR) Human Gene Knockout Kit (CRISPR)

CAT#: KN210359BN

SRR - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Donor DNA: mBFP-Neo
• Symbol: Serine racemase
• Locus ID: 63826
• Components:

  KN210359G1, Serine racemase gRNA vector 1 in pCas-Guide CRISPR vector

  KN210359G2, Serine racemase gRNA vector 2 in pCas-Guide CRISPR vector

  KN210359BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001304803, NM_021947
• UniProt ID: Q9GZT4
• Synonyms: ILV1; ISO1
• Summary: Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.[UniProtKB/Swiss-Prot Function]