Human beta V Tubulin (TUBB) activation kit by CRISPRa

CAT#: GA116428

TUBB CRISPRa kit - CRISPR gene activation of human tubulin beta class I

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: TUBB
• Locus ID: 203068
• Kit Components:

  GA116428G1, beta V Tubulin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116428G2, beta V Tubulin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116428G3, beta V Tubulin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001293212, NM_001293213, NM_001293214, NM_001293215, NM_001293216, NM_178014, NR_120608
• UniProt ID: P07437
• Synonyms: CDCBM6; CSCSC1; M40; OK/SW-cl.56; TUBB1; TUBB5
• Summary: This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1, 6, 7, 8, 9, and 13. [provided by RefSeq, Jun 2014]