Human Gastrokine 2 (GKN2) activation kit by CRISPRa

CAT#: GA116351

GKN2 CRISPRa kit - CRISPR gene activation of human gastrokine 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: GKN2
• Locus ID: 200504
• Kit Components:

  GA116351G1, Gastrokine 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116351G2, Gastrokine 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116351G3, Gastrokine 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_182536
• UniProt ID: Q86XP6
• Synonyms: BRICD1B; GDDR; PRO813; TFIZ1; VLTI465
• Summary: The secretory protein encoded by this gene is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine-1. This gene may be a tumor suppressor gene, as its expression is markedly decreased in gastric cancer tissues. The encoded protein interacts with gastrokine-1 and regulates homeostasis of the gastric mucosa. [provided by RefSeq, Dec 2015]