Human IL17F activation kit by CRISPRa

CAT#: GA114365

IL17F CRISPRa kit - CRISPR gene activation of human interleukin 17F

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: IL17F
• Locus ID: 112744
• Kit Components:

  GA114365G1, IL17F gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114365G2, IL17F gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114365G3, IL17F gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_052872, NM_172343
• UniProt ID: Q96PD4
• Synonyms: CANDF6; IL-17F; ML-1; ML1
• Summary: The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]