Human MERTK activation kit by CRISPRa

CAT#: GA107137

MERTK CRISPRa kit - CRISPR gene activation of human MER proto-oncogene, tyrosine kinase

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: MERTK
• Locus ID: 10461
• Kit Components:

  GA107137G1, MERTK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107137G2, MERTK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107137G3, MERTK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006343
• UniProt ID: Q12866
• Synonyms: c-mer; MER; RP38
• Summary: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008]