Human CD94 (KLRD1) activation kit by CRISPRa

CAT#: GA102593

KLRD1 CRISPRa kit - CRISPR gene activation of human killer cell lectin like receptor D1

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: KLRD1
• Locus ID: 3824
• Kit Components:

  GA102593G1, CD94 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA102593G2, CD94 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA102593G3, CD94 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001114396, NM_002262, NM_007334, NM_001351060, NM_001351062, NM_001351063, NR_147038, NR_147039, NR_147040
• UniProt ID: Q13241
• Synonyms: CD94
• Summary: Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]