Human Cannabinoid Receptor II (CNR2) activation kit by CRISPRa

CAT#: GA100889

CNR2 CRISPRa kit - CRISPR gene activation of human cannabinoid receptor 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: CNR2
• Locus ID: 1269
• Kit Components:

  GA100889G1, Cannabinoid Receptor II gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100889G2, Cannabinoid Receptor II gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100889G3, Cannabinoid Receptor II gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001841
• UniProt ID: P34972
• Synonyms: CB-2; CB2; CX5
• Summary: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]