NFAT1 (NFATC2) (NM_173091) Human Untagged Clone

CAT#: SC306788

NFATC2 (untagged)-Human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (NFATC2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NFAT1
• Synonyms: NFAT1; NFATP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_173091 edited
  AGCAGGAAGCTCGCGCCGCCGTCGCCGCCGCCGCTCAGCTTCCCCGGGCGCGTCCAGGAC
  CCGCTGCGCCAGGCGCGCCGTCCCCGGACCCGGCGTGCGTCCCTACGAGGAAAGGGACCC
  CGCCGCTCGAGCCGCCTCCGCCAGCCCCACTGCGAGGGGTCCCAGAGCCAGCCGCGCCCG
  CCCTCGCCCCCGGCCCCGCAGCCTTCCCGCCCTGCGCGCCATGAACGCCCCCGAGCGGCA
  GCCCCAACCCGACGGCGGGGACGCCCCAGGCCACGAGCCTGGGGGCAGCCCCCAAGACGA
  GCTTGACTTCTCCATCCTCTTCGACTATGAGTATTTGAATCCGAACGAAGAAGAGCCGAA
  TGCACATAAGGTCGCCAGCCCACCCTCCGGACCCGCATACCCCGATGATGTCCTGGACTA
  TGGCCTCAAGCCATACAGCCCCCTTGCTAGTCTCTCTGGCGAGCCCCCCGGCCGATTCGG
  AGAGCCGGATAGGGTAGGGCCGCAGAAGTTTCTGAGCGCGGCCAAGCCAGCAGGGGCCTC
  GGGCCTGAGCCCTCGGATCGAGATCACTCCGTCCCACGAACTGATCCAGGCAGTGGGGCC
  CCTCCGCATGAGAGACGCGGGCCTCCTGGTGGAGCAGCCGCCCCTGGCCGGGGTGGCCGC
  CAGCCCGAGGTTCACCCTGCCCGTGCCCGGCTTCGAGGGCTACCGCGAGCCGCTTTGCTT
  GAGCCCCGCTAGCAGCGGCTCCTCTGCCAGCTTCATTTCTGACACCTTCTCCCCCTACAC
  CTCGCCCTGCGTCTCGCCCAATAACGGCGGGCCCGACGACCTGTGTCCGCAGTTTCAAAA
  CATCCCTGCTCATTATTCCCCCAGAACCTCGCCAATAATGTCACCTCGAACCAGCCTCGC
  CGAGGACAGCTGCCTGGGCCGCCACTCGCCCGTGCCCCGTCCGGCCTCCCGCTCCTCATC
  GCCTGGTGCCAAGCGGAGGCATTCGTGCGCCGAGGCCTTGGTTGCCCTGCCGCCCGGAGC
  CTCACCCCAGCGCTCCCGGAGCCCCTCGCCGCAGCCCTCATCTCACGTGGCACCCCAGGA
  CCACGGCTCCCCGGCTGGGTACCCCCCTGTGGCTGGCTCTGCCGTGATCATGGATGCCCT
  GAACAGCCTCGCCACGGACTCGCCTTGTGGGATCCCCCCCAAGATGTGGAAGACCAGCCC
  TGACCCCTCGCCGGTGTCTGCCGCCCCATCCAAGGCCGGCCTGCCTCGCCACATCTACCC
  GGCCGTGGAGTTCCTGGGGCCCTGCGAGCAGGGCGAGAGGAGAAACTCGGCTCCAGAATC
  CATCCTGCTGGTTCCGCCCACTTGGCCCAAGCCGCTGGTGCCTGCCATTCCCATCTGCAG
  CATCCCAGTGACTGCATCCCTCCCTCCACTTGAGTGGCCGCTGTCCAGTCAGTCAGGCTC
  TTACGAGCTGCGGATCGAGGTGCAGCCCAAGCCACATCACCGGGCCCACTATGAGACAGA
  AGGCAGCCGAGGGGCTGTCAAAGCTCCAACTGGAGGCCACCCTGTGGTTCAGCTCCATGG
  CTACATGGAAAACAAGCCTCTGGGACTTCAGATCTTCATTGGGACAGCTGATGAGCGGAT
  CCTTAAGCCGCACGCCTTCTACCAGGTGCACCGAATCACGGGGAAAACTGTCACCACCAC
  CAGCTATGAGAAGATAGTGGGCAACACCAAAGTCCTGGAGATACCCTTGGAGCCCAAAAA
  CAACATGAGGGCAACCATCGACTGTGCGGGGATCTTGAAGCTTAGAAACGCCGACATTGA
  GCTGCGGAAAGGCGAGACGGACATTGGAAGAAAGAACACGCGGGTGAGACTGGTTTTCCG
  AGTTCACATCCCAGAGTCCAGTGGCAGAATCGTCTCTTTACAGACTGCATCTAACCCCAT
  CGAGTGCTCCCAGCGATCTGCTCACGAGCTGCCCATGGTTGAAAGACAAGACACAGACAG
  CTGCCTGGTCTATGGCGGCCAGCAAATGATCCTCACGGGGCAGAACTTTACATCCGAGTC
  CAAAGTTGTGTTTACTGAGAAGACCACAGATGGACAGCAAATTTGGGAGATGGAAGCCAC
  GGTGGATAAGGACAAGAGCCAGCCCAACATGCTTTTTGTTGAGATCCCTGAATATCGGAA
  CAAGCATATCCGCACACCTGTAAAAGTGAACTTCTACGTCATCAATGGGAAGAGAAAACG
  AAGTCAGCCTCAGCACTTTACCTACCACCCAGTCCCAGCCATCAAGACGGAGCCCACGGA
  TGAATATGACCCCACTCTGATCTGCAGCCCCACCCATGGAGGCCTGGGGAGCCAGCCTTA
  CTACCCCCAGCACCCGATGGTGGCCGAGTCCCCCTCCTGCCTCGTGGCCACCATGGCTCC
  CTGCCAGCAGTTCCGCACGGGGCTCTCATCCCCTGACGCCCGCTACCAGCAACAGAACCC
  AGCGGCCGTACTCTACCAGCGGAGCAAGAGCCTGAGCCCCAGCCTGCTGGGCTATCAGCA
  GCCGGCCCTCATGGCCGCCCCGCTGTCCCTTGCGGACGCTCACCGCTCTGTGCTGGTGCA
  CGCCGGCTCCCAGGGCCAGAGCTCAGCCCTGCTCCACCCCTCTCCGACCAACCAGCAGGC
  CTCGCCTGTGATCCACTACTCACCCACCAACCAGCAGCTGCGCTGCGGAAGCCACCAGGA
  GTTCCAGCACATCATGTACTGCGAGAATTTCGCACCAGGCACCACCAGACCTGGCCCGCC
  CCCGGTCAGTCAAGGTCAGAGGCTGAGCCCGGGTTCCTACCCCACAGTCATTCAGCAGCA
  GAATGCCACGAGCCAAAGAGCCGCCAAAAACGGACCCCCGGTCAGTGACCAAAAGGAAGT
  ATTACCTGCGGGGGTGACCATTAAACAGGAGCAGAACTTGGACCAGACCTACTTGGATGA
  TGTTAATGAAATTATCAGGAAGGAGTTTTCAGGACCTCCTGCCAGAAATCAGACGTAAAA
  GAAGCCATTATAGCAAGACACCTTCTGTATCTGACCCCTCGGAGCCCTCCACAGCCCCTC
  ACCTTCTGTCTCCTTTCATGTTCATCTCCCAGCCCGGAGTCCACACGCGGATCAATGTAT
  GGGCACTAAGCGGACTCTCACTTAAGGAGCTCGCCACCTCCCTCTAAACACCAGAGAGAA
  CTCTTCTTTTCGGTTTATGTTTTAAATCCCAGAGAGCATCCTGGTTGATCTTAATGGTGT
  TCCGTCCAAATAGTAAGCACCTGCTGACCAAAAGCACATTCTACATGAGACAGGACACTG
  GAACTCTCCTGAGAACAGAGTGACTGGAGCTTGGGGGGATGGACGGGGGACAGAAGATGT
  GGGCACTGTGATTAAACCCCAGCCCTTGCGTTCGTTTTTCCAGGTCACAGATACAGCTCC
  TGTACCTTTTGAAGGCAAGGAGTTCTCAGAGCAACCAAAGGAACGTGACCCAAGAGCCCA
  GCTTACAGGCTGAAGAAACCCAAAACCCTCGATAGAGACAGAAACTGAACTGTCAGTCCT
  TAGAGCTCGCCCAGTCCATGCCACAACTGGGCCACAGCTAAAGCTTTATTTTTGAATTCT
  CATTCCAAAACCAAACTGTCTTGCCCAGACAAGATCACCTGTTAAGACTTCTTGGCGTTA
  AGTTATGACATGTATACGCGTTTGTTATTATTATTTTTTCTGCTTTAAAAGGCTGACCAG
  GGCACCTAGCCCTGGAGCTGTCTTGGCGAGCTGTTCTTTAACCCCTGCAGCACGCAGTCC
  TGCTAACACAATTTCCATAGACTTGGGGGGCTGACCCAGGCTGCAGAGAGCAAGCACCTG
  TCTGCTGCAGCTGTACAACCTGGATGCTTTGCAAGGTTCCGGCTTGCTTTCTTCCTAGCA
  GCCAGAGTGCTTTTCCGTAAAGCGGTGGAGAATCTCAAGCATGTGCATTTAATTGAGGAA
  TAGCAGAAGGGCTAAAGCAACCAAGAAAAGAAGTGTGGGTATTTTTGTTAAGTAAAACAG
  CCCAAGTGCTTCTGGAGGTGGGTTTCTACCAAGATAGAGGAAAAGGGCTGAATTCCCTCT
  AAGTGGGACAGCCGAGCTCAGGATGTGCTTCCCAGCTTCACTGGTTAATTTGACCTGAAC
  CTATTTAAAGATCCCTTCTGCCCCTGAAGACCTATCCGCACTCAAATTCTAACATGAAGA
  AATCTACTCGAATGCATCCTTTACTTTGAATGAGCTCTATTCGGTTGCATGTTATATGTG
  ATTTCCTTCCTCCCAACTGTTTCCACTGAGCGCACCCACAGTCTCCCCTAGTCTTCCTCT
  GTGGGTGTGATTTTTGTGATTTTTACAAACAAAACCCTTGAAGTTCTTGGCAGATGTGTT
  TGTTTCTGTTTGCATGTACTGCAGATACCCCAGGACAAGCGGGGGATTCATTTTTCAGCC
  ATTCAGTTGTTTCCTCAATAATCCGCAGCAAAGTGAAAATATTCTTAGCACTCAGACTGT
  ACTTAGAGTGTTTTCTCAGTCCAGTCTGTACAGTCTGTAGGCAGAAGGCCTCAGAAGAAA
  GTCATGGCCACTCAGTGCCCACTGTGGGCTTTGTAAGTCCTGGCTCTCCCGTCAAGGTTA
  CCCAGAGGTAAAAGCTTCCTGGGAGTGGGGCCAGGTGTGTTTGGCACTCCAGATAGAAGG
  CAAAATGCTCAGATTCGGGCCTGTGCACTTGTATGCAACCTGTCGGTCGATACCTAGCAT
  TTATTTTTCCCTGACAATGAACGACCTTTCCCTCACCCACCCTAAGCTCAAAGAGTTTAG
  CAAAATTCTCTTTTAAATAAACAGAATGCCAGTAAGAGGTTGACCCCTACCATGGAACTT
  CTGGGATGCTAAATACTTCCTCATGAACAAAACAAGTTCCTTATTATAAGTTCCTTATAC
  TAGCAGCTTCACCTAAAGAATTTTCTCTCCAGCAATATTGACTTCACTGGGGAAAAGCCA
  AGAGTGTGTGGTGAGTGATTTGTTCTCACTCGACCTGGCTAGGACTGGCTAGGAGCTGTT
  TTTTGTACATGAGGGAATTTGGGCTTTCCTCAGTTATCTGAATGTTTTACCCAAGTGCCT
  TCCTGCTATTGTAGCAAAGTAGCTCAGCTTCCTTGTCCACAGGGTGAAAAAGGACTAATG
  CATTTTCCATCAGTTTTCTAACTATGTTAGCAAAAAGGGCCTCCTGGTAGCTCAACCTCC
  TGTACGCGTGTATGTGTGTAATACACACACAAATAAACCCCTCTGTTTTTCTAAGACATC
  TTAGCTGGATATTATAGGAAGCACTTTCATAAACAACTGTAACAAATCGCAAAGGAAAGA
  GAAACAAAAGCATTAGATTTGAGACATAAACAGGCAAGAGAAAGTGTATTAGGAACTGAC
  AGCTATCAAGGAAGTTTTGTCAGTTACAAATGCTAGGAGGAAATTTTGCCAGGAAGGATG
  GCTCATGAAATATTTCCAGTACGGGAAGAGGCAATAAGATCCTCTAAGAGAATGAGAAAG
  TAGGGGTGTCTAAATGGTAAAGATGGGTGTGTTGCACGTGTGTTAGAAGGATCTCAGTTG
  AGTGAAGGTTTGCACTGCTACATCTAAGTTAATGTAAATATGTAGCACTCTGACAGGTCT
  ACCGTGTTGCTGAATGTAGTATATTTCCAAAGTTTGCAAGTCTTCCTGTATTGTACAAAG
  ATGCTGCTGCTTGATAATATGTATAGCAATCCAGATTAGTATGTTATTAAATTTTATTTT
  CTTACCTGTATTTTTATGCTTTTTACCTGTCCTCAAAATATTACACCCCTGTTGGAATTA
  GATTTATATTTATAAATGGTCAGAAATCTTTTTAAGTGTCTCTTTTTACACATAGGTTGA
  TTTTTTTTTTCTTAAGAGAAATGATGTATTCTTGAAACATTTGTTACTCATTCCAGGAAA
  CAAAAACCCATATAATAAAACCCCCACTCAGAGCCTGTTAGTCACCTCTCTAGAAGATGG
  CATCTCAGGAGAAGGAATGGCTTTGTGGAAGAAGGAATCACCTTTTTCTTGCTCAAGAAT
  TATGCTGACTTCAGCCCTGAGCCTGGATCTGGTCACTGAGAATCATCAAGTGTCTAGATC
  CTCCCCCCAAAATAACTAATTTAGTAGGTGATTTTGATTTTAAAAAATTGACACCAAAAC
  CCTGCCTGCATTGTAATGGAATTCGAAAAGAATTCATGTTCACAGAACTCAACGTTCAGG
  CTAATATTTACAGAAGGGACCAAATCTAAATCCTGGTAGATAACTCCTGTATGCTTTATC
  CAAAGGACACCCACAGTTTTCCAGCATAGATATAACCAAGGATGAATTGATTCCTTCAAA
  GAACTGGGAGGCACGGATATTGCATTTTTTGTTTACATCCAGTAGCCAAGACGCCTCAGT
  GAGCCAGTCTTGGGCAGAGGCTGTCACATTTAGGCAGATTGGAAGTTGGTATGTTCTAAT
  TCTCACTCTGGACTACAGTGAGGCTGAATTTATCATGTCAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_173091
• Insert Size: 3100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_173091.2, NP_775114.1
• RefSeq Size: 3166 bp
• RefSeq ORF: 2778 bp
• Locus ID: 4773
• UniProt ID: Q13469
• Cytogenetics: 20q13.2
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Axon guidance, B cell receptor signaling pathway, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway
• Gene Summary: This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]
  Transcript Variant: This variant (2) encodes the longest isoform (C). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.