ALDH3B2 (NM_000695) Human Untagged Clone

CAT#: SC119708

ALDH3B2 (untagged)-Human aldehyde dehydrogenase 3 family, member B2 (ALDH3B2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ALDH3B2
• Synonyms: ALDH8
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119708 sequence for NM_000695 edited (data generated by NextGen Sequencing)
  ATGAAGGATGAACCACGGTCCACGAACCTGTTCATGAAGCTGGACTCGGTCTTCATCTGG
  AAGGAACCCTTTGGCCTGGTCCTCATCATCGCACCCTGGAACTACCCACTGAACCTGACC
  CTGGTGCTCCTGGTGGGCGCCCTCGCCGCAGGGAATTGCGTGGTGCTGAAGCCGTCAGAA
  ATCAGCCAGGGCACAGAGAAGGTCCTGGCTGAGGTGCTGCCCCAGTACCTGGACCAGAGC
  TGCTTTGCCGTGGTGCTGGGCGGACCCCAGGAGACAGGGCAGCTGCTAGAGCACAAGTTG
  GACTACATCTTCTTCACAGGGAGCCCTCGTGTGGGCAAGATTGTCATGACTGCTGCCACC
  AAGCACCTGACGCCTGTCACCCTGGAGCTGGGGGGCAAGAACCCCTGCTACGTGGACGAC
  AACTGCGACCCCCAGACCGTGGCCAACCGCGTGGCCTGGTTCTGCTACTTCAATGCCGGC
  CAGACCTGCGTGGCCCCTGACTACGTCCTGTGCAGCCCCGAGATGCAGGAGAGGCTGCTG
  CCCGCCCTGCAGAGCACCATCACCCGTTTCTATGGCGACGACCCCCAGAGCTCCCCAAAC
  CTGGGCCGCATCATCAACCAGAAACAGTTCCAGCGGCTGCGGGCATTGCTGGGCTGCGGC
  CGCGTGGCCATTGGGGGCCAGAGCAACGAGAGCGATCGCTACATCGCCCCCACGGTGCTG
  GTGGACGTGCAGGAGACGGAGCCTGTGATGCAGGAGGAGATCTTCGGGCCCATCCTGCCC
  ATCGTGAACGTGCAGAGCGTGGACGAGGCCATCAAGTTCATCAACCGGCAGGAGAAGCCC
  CTGGCCCTGTACGCCTTCTCCAACAGCAGCCAGGTTGTGAACCAGATGCTGGAGCGGACC
  AGCAGCGGCAGCTTTGGAGGCAATGAGGGCTTCACCTACATATCTCTGCTGTCCGTGCCA
  TTCGGGGGAGTCGGCCACAGTGGGATGGGCCGGTACCACGGCAAGTTCACCTTCGACACC
  TTCTCCCACCACCGCACCTGCCTGCTCGCCCCCTCCGGCCTGGAGAAATTAAAGGAGATC
  CGCTACCCACCCTATACCGACTGGAACCAGCAGCTGTTACGCTGGGGCATGGGCTCCCAG
  AGCTGCACCCTCCTGTGA
  
  Clone variation with respect to NM_000695.3
  155 g=>a;1082 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000695 unedited
  CTTGGGTTTTGTAACCCCCACTTCTAGTAGGGCGGCACAAAACTTCGGCACGAGGCACGG
  GAGTTGGTTTGGGAGCTGCCAGGCTCCTGGGAGGATCGCAGTCAGCAGAGCAGGGCTGAG
  GCCTGGGGGTAGGAGCAGAGCCTGCGCATCTGGAGGCAGCATGTCCAAGAAAGGGAGTGG
  AGGTGCAGCGAAGGACCCAGGGGCAGAGCCCACGCTGTTGTTGGACCCCTTCGAGGACAC
  GCTGCGGCGGCTGCGTGAGGCCTTCAACTGAGGGCGCACGCGGCCGGCCGAGTTCCGGGC
  TGCGCAGCTCCAGGGCCTGGGCCACTTCCTTCAAGAAAACAAGCAGCTTCTGCGCGACGT
  GCTGGCCCAGGACCTGCATAAGCCAGCTTTCGAGGCAGACATATCTGAGCTCATCCTTTG
  CCAGAACGAGGTTGACTACGCTCTCAAGAACCTTCAGGCCTGGATGAAGGATGAACCACG
  GTCCACGAACCTGTTCATGAAGCTGGACTCGGTCTTCATCTGGAAGGAACCCTTTGGCCT
  GGTCCTCATCATCGCACCCTGGAACTACCCACTGAACCTGACCCTGGTGCTCCTGGTGGG
  CGCCCTCGCCGCATGGAATTGCGTGGTGCTGAAGCCGTCAGATATCAGCCAGGGCACAGA
  GAATGTCCTGGCTGATGTGCTGCCCCAGTACCTGGACCAGAGCTGCTTTGCCGTGGTGCT
  GGGCGGACCCCNAGAGACAGGGCAGCTGCTAGAGCACAAGTAGGACTACATCTTNCTCAC
  AGGGAGCCCTCGTGTGGGCAAGATTGTCATGACTGCTGCCACAAGCACCTGACGCCTGTC
  ACCCCTGGAGCTGGGGGGGCAAGACCCCTGCTACGTGGACGATCACTGCGACNCCCAGAC
  GTGGGCCATCGCGTGGGCTGGTNCTGCTAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000695 unedited
  GGCACGCTATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTAGGTTTTCCAAAACAAATGAATTTATTTGGGAGGAGCAAAGGATTCCTATCTGGGCTA
  TGAGTGCTTGGAAGGATCCCAGGCATACACAGAGGGCCACAGCCAAGGGGAAGCTTTTAA
  AGGACAAAAGTCCATGTAAGCAGCTTTTAAACAAGGGTTGTAATTTTTTTCTGATCCCAA
  GAGTTGGCGATGGTTTTCTGGGGGAAACGGCCGGGGTAGGTAAACATCTGCAGCTCATTT
  GGAATACTACAGTCTTGAGGACGTGCTTTCCATACCCCCTGTGTCTGGTCTACATGCAGG
  CGTGTCTTGGGATAAATCCTGTTACGGGCATGTGTGTGTGAGGGCTTCTATGTGGCCCCC
  CGACTCCATTTTATTAAAGTTTGGCATAAGTGACTCCATTTTGGTTCCAGCAACTTTCAC
  ATAAGGAAACTGAGGCTCAAAGAAGTCAAGGGACTTGCCCCCAGGTCCCACTAACACTGT
  GCAGTGGAGTGATGCAAACCCCAGTTTTCCCAATGGATGGACCTGCTGTGGGTGAATGCA
  AGGTGCGGTGTGAACCAAAGGGGTGGTGCACAAACCATTGTGGGATGTGAGAAGATCCCT
  GGGGGAAGCAATGCTTGTGCATTTGGATGGGGCAAAGTGGAAATCCCCTTGGCCTAAAGG
  GAAACCAAAGCCCGGAAGGCTCCACCTCTCAACCGTTAAGGCTTGAGCCCTAAAAAGGCG
  GGCCCTGGTTTTTCCAAGGGGACCCTGCCCCTGGAATGGGCCTGGCCAACCTGACCAAAG
  AGCAAGGGCCTAATTTGGGAGGGGGGGGGAATAAAACCCTGGTTTTTTTGGCGCCTTTGC
  CCTTTTAAACGCGTCCCAAAAAAACAAAACTTCTTTACACCTGCGGCGGATGATATTGTA
  AT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000695
• Insert Size: 2620 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000695.3, NP_000686.2
• RefSeq Size: 2660 bp
• RefSeq ORF: 1158 bp
• Locus ID: 222
• Cytogenetics: 11q13.2
• Domains: aldedh
• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - cytochrome P450, Glycolysis / Gluconeogenesis, Histidine metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Phenylalanine metabolism, Tyrosine metabolism
• Gene Summary: This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this particular family member is over 10 kb in length. Altered methylation patterns at this locus have been observed in spermatozoa derived from patients exhibiting reduced fecundity. [provided by RefSeq, Aug 2017]
  Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.